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Facilitating drug delivery in the central nervous system by opening the blood-cerebrospinal fluid barrier with a single low energy shockwave pulse

BACKGROUND: The blood-cerebrospinal fluid (CSF) barrier (BCSFB) is critically important to the pathophysiology of the central nervous system (CNS). However, this barrier prevents the safe transmission of beneficial drugs from the blood to the CSF and thus the spinal cord and brain, limiting their ef...

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Detalles Bibliográficos
Autores principales: Kung, Yi, Chen, Kuan-Yu, Liao, Wei-Hao, Hsu, Yi-Hua, Wu, Chueh-Hung, Hsiao, Ming-Yen, Huang, Abel P.-H., Chen, Wen-Shiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740485/
https://www.ncbi.nlm.nih.gov/pubmed/34991647
http://dx.doi.org/10.1186/s12987-021-00303-x