HobPre: accurate prediction of human oral bioavailability for small molecules

Human oral bioavailability (HOB) is a key factor in determining the fate of new drugs in clinical trials. HOB is conventionally measured using expensive and time-consuming experimental tests. The use of computational models to evaluate HOB before the synthesis of new drugs will be beneficial to the...

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Detalles Bibliográficos
Autores principales: Wei, Min, Zhang, Xudong, Pan, Xiaolin, Wang, Bo, Ji, Changge, Qi, Yifei, Zhang, John Z. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740492/
https://www.ncbi.nlm.nih.gov/pubmed/34991690
http://dx.doi.org/10.1186/s13321-021-00580-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740492/
https://www.ncbi.nlm.nih.gov/pubmed/34991690
http://dx.doi.org/10.1186/s13321-021-00580-6

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