Lipid bilayer induces contraction of the denatured state ensemble of a helical-bundle membrane protein

Defining the denatured state ensemble (DSE) and disordered proteins is essential to understanding folding, chaperone action, degradation, and translocation. As compared with water-soluble proteins, the DSE of membrane proteins is much less characterized. Here, we measure the DSE of the helical membr...

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Detalles Bibliográficos
Autores principales: Gaffney, Kristen A., Guo, Ruiqiong, Bridges, Michael D., Muhammednazaar, Shaima, Chen, Daoyang, Kim, Miyeon, Yang, Zhongyu, Schilmiller, Anthony L., Faruk, Nabil F., Peng, Xiangda, Jones, A. Daniel, Kim, Kelly H., Sun, Liangliang, Hubbell, Wayne L., Sosnick, Tobin R., Hong, Heedeok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740594/
https://www.ncbi.nlm.nih.gov/pubmed/34969836
http://dx.doi.org/10.1073/pnas.2109169119

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