Leveraging cell-type-specific regulatory networks to interpret genetic variants in abdominal aortic aneurysm

Abdominal aortic aneurysm (AAA) is a common degenerative cardiovascular disease whose pathobiology is not clearly understood. The cellular heterogeneity and cell-type-specific gene regulation of vascular cells in human AAA have not been well-characterized. Here, we performed analysis of whole-genome...

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Detalles Bibliográficos
Autores principales: Ma, Shining, Chen, Xi, Zhu, Xiang, Tsao, Philip S., Wong, Wing Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Physical Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740683/
https://www.ncbi.nlm.nih.gov/pubmed/34930827
http://dx.doi.org/10.1073/pnas.2115601119

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