A virus-specific monocyte inflammatory phenotype is induced by SARS-CoV-2 at the immune–epithelial interface

Infection by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) provokes a potentially fatal pneumonia with multiorgan failure, and high systemic inflammation. To gain mechanistic insight and ferret out the root of this immune dysregulation, we modeled, by in vitro coculture, the interacti...

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Detalles Bibliográficos
Autores principales: Leon, Juliette, Michelson, Daniel A., Olejnik, Judith, Chowdhary, Kaitavjeet, Oh, Hyung Suk, Hume, Adam J., Galván-Peña, Silvia, Zhu, Yangyang, Chen, Felicia, Vijaykumar, Brinda, Yang, Liang, Crestani, Elena, Yonker, Lael M., Knipe, David M., Mühlberger, Elke, Benoist, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740714/
https://www.ncbi.nlm.nih.gov/pubmed/34969849
http://dx.doi.org/10.1073/pnas.2116853118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740714/
https://www.ncbi.nlm.nih.gov/pubmed/34969849
http://dx.doi.org/10.1073/pnas.2116853118

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