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A virus-specific monocyte inflammatory phenotype is induced by SARS-CoV-2 at the immune–epithelial interface
Infection by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) provokes a potentially fatal pneumonia with multiorgan failure, and high systemic inflammation. To gain mechanistic insight and ferret out the root of this immune dysregulation, we modeled, by in vitro coculture, the interacti...
Autores principales: | Leon, Juliette, Michelson, Daniel A., Olejnik, Judith, Chowdhary, Kaitavjeet, Oh, Hyung Suk, Hume, Adam J., Galván-Peña, Silvia, Zhu, Yangyang, Chen, Felicia, Vijaykumar, Brinda, Yang, Liang, Crestani, Elena, Yonker, Lael M., Knipe, David M., Mühlberger, Elke, Benoist, Christophe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740714/ https://www.ncbi.nlm.nih.gov/pubmed/34969849 http://dx.doi.org/10.1073/pnas.2116853118 |
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