Phospholipase A2 inhibitor and LY6/PLAUR domain-containing protein PINLYP regulates type I interferon innate immunity

Type I interferons (IFNs) are the first frontline of the host innate immune response against invading pathogens. Herein, we characterized an unknown protein encoded by phospholipase A2 inhibitor and LY6/PLAUR domain-containing (PINLYP) gene that interacted with TBK1 and induced type I IFN in a TBK1-...

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Detalles Bibliográficos
Autores principales: Liu, Zhongshun, Jiang, Congwei, Lei, Zhangmengxue, Dong, Sihan, Kuang, Linlin, Huang, Chenxu, Gao, Ying, Liu, Mu, Xiao, Hui, Legembre, Patrick, Jung, Jae U., Liang, Huaping, Liang, Xiaozhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740751/
https://www.ncbi.nlm.nih.gov/pubmed/34969857
http://dx.doi.org/10.1073/pnas.2111115119

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