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Reflex Anuria: A Complication of Hyperthermic Intraperitoneal Chemotherapy
Reflex anuria (RA) is a rare cause of abrupt reduction of urine output following trauma, irritation, or painful stimuli to the kidneys, ureters, or surrounding organs. The mechanism of RA is a reflex spasm of both ureters and/or renal arterioles. It is a well-documented complication of colorectal su...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740905/ https://www.ncbi.nlm.nih.gov/pubmed/35018265 http://dx.doi.org/10.7759/cureus.20269 |
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author | Fayed, Mohamed Banerjee, Gargi Feng, Danni Chen, Irene |
author_facet | Fayed, Mohamed Banerjee, Gargi Feng, Danni Chen, Irene |
author_sort | Fayed, Mohamed |
collection | PubMed |
description | Reflex anuria (RA) is a rare cause of abrupt reduction of urine output following trauma, irritation, or painful stimuli to the kidneys, ureters, or surrounding organs. The mechanism of RA is a reflex spasm of both ureters and/or renal arterioles. It is a well-documented complication of colorectal surgeries and gynecological surgeries which involve placement of a ureteric stent for ureteric identification and prevention of injury. RA and post-renal obstruction can both be complications of intraperitoneal hyperthermic chemotherapy (HIPEC) in patients who are undergoing surgery for colorectal cancer and peritoneal carcinomatosis. HIPEC procedure can lead to inflammation of the entire abdomen, including the ureters. This inflammation can result in hematuria that can form clots along the urinary tract and cause post-renal obstruction. The inflammation can also result in RA. It is essential to maintain high urine output during the early postoperative period to prevent clots and the ensuing post renal obstruction. It is also important to identify RA and maintain a low threshold to treat it by placing ureteric stents even in the absence of overt bilateral hydronephrosis. |
format | Online Article Text |
id | pubmed-8740905 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-87409052022-01-10 Reflex Anuria: A Complication of Hyperthermic Intraperitoneal Chemotherapy Fayed, Mohamed Banerjee, Gargi Feng, Danni Chen, Irene Cureus Urology Reflex anuria (RA) is a rare cause of abrupt reduction of urine output following trauma, irritation, or painful stimuli to the kidneys, ureters, or surrounding organs. The mechanism of RA is a reflex spasm of both ureters and/or renal arterioles. It is a well-documented complication of colorectal surgeries and gynecological surgeries which involve placement of a ureteric stent for ureteric identification and prevention of injury. RA and post-renal obstruction can both be complications of intraperitoneal hyperthermic chemotherapy (HIPEC) in patients who are undergoing surgery for colorectal cancer and peritoneal carcinomatosis. HIPEC procedure can lead to inflammation of the entire abdomen, including the ureters. This inflammation can result in hematuria that can form clots along the urinary tract and cause post-renal obstruction. The inflammation can also result in RA. It is essential to maintain high urine output during the early postoperative period to prevent clots and the ensuing post renal obstruction. It is also important to identify RA and maintain a low threshold to treat it by placing ureteric stents even in the absence of overt bilateral hydronephrosis. Cureus 2021-12-08 /pmc/articles/PMC8740905/ /pubmed/35018265 http://dx.doi.org/10.7759/cureus.20269 Text en Copyright © 2021, Fayed et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Urology Fayed, Mohamed Banerjee, Gargi Feng, Danni Chen, Irene Reflex Anuria: A Complication of Hyperthermic Intraperitoneal Chemotherapy |
title | Reflex Anuria: A Complication of Hyperthermic Intraperitoneal Chemotherapy |
title_full | Reflex Anuria: A Complication of Hyperthermic Intraperitoneal Chemotherapy |
title_fullStr | Reflex Anuria: A Complication of Hyperthermic Intraperitoneal Chemotherapy |
title_full_unstemmed | Reflex Anuria: A Complication of Hyperthermic Intraperitoneal Chemotherapy |
title_short | Reflex Anuria: A Complication of Hyperthermic Intraperitoneal Chemotherapy |
title_sort | reflex anuria: a complication of hyperthermic intraperitoneal chemotherapy |
topic | Urology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740905/ https://www.ncbi.nlm.nih.gov/pubmed/35018265 http://dx.doi.org/10.7759/cureus.20269 |
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