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Chronic Kidney Disease Testing Among Primary Care Patients With Type 2 Diabetes Across 24 U.S. Health Care Organizations

OBJECTIVE: Clinical guidelines for people with diabetes recommend chronic kidney disease (CKD) testing at least annually using estimated glomerular filtration rate (eGFR) and urinary albumin-to-creatinine ratio (uACR). We aimed to understand CKD testing among people with type 2 diabetes in the U.S....

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Autores principales: Stempniewicz, Nikita, Vassalotti, Joseph A., Cuddeback, John K., Ciemins, Elizabeth, Storfer-Isser, Amy, Sang, Yingying, Matsushita, Kunihiro, Ballew, Shoshana H., Chang, Alex R., Levey, Andrew S., Bailey, Robert A., Fishman, Jesse, Coresh, Josef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740923/
https://www.ncbi.nlm.nih.gov/pubmed/34233925
http://dx.doi.org/10.2337/dc20-2715
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author Stempniewicz, Nikita
Vassalotti, Joseph A.
Cuddeback, John K.
Ciemins, Elizabeth
Storfer-Isser, Amy
Sang, Yingying
Matsushita, Kunihiro
Ballew, Shoshana H.
Chang, Alex R.
Levey, Andrew S.
Bailey, Robert A.
Fishman, Jesse
Coresh, Josef
author_facet Stempniewicz, Nikita
Vassalotti, Joseph A.
Cuddeback, John K.
Ciemins, Elizabeth
Storfer-Isser, Amy
Sang, Yingying
Matsushita, Kunihiro
Ballew, Shoshana H.
Chang, Alex R.
Levey, Andrew S.
Bailey, Robert A.
Fishman, Jesse
Coresh, Josef
author_sort Stempniewicz, Nikita
collection PubMed
description OBJECTIVE: Clinical guidelines for people with diabetes recommend chronic kidney disease (CKD) testing at least annually using estimated glomerular filtration rate (eGFR) and urinary albumin-to-creatinine ratio (uACR). We aimed to understand CKD testing among people with type 2 diabetes in the U.S. RESEARCH DESIGN AND METHODS: Electronic health record data were analyzed from 513,165 adults with type 2 diabetes receiving primary care from 24 health care organizations and 1,164 clinical practice sites. We assessed the percentage of patients with both one or more eGFRs and one or more uACRs and each test individually in the 1, 2, and 3 years ending September 2019 by health care organization and clinical practice site. Elevated albuminuria was defined as uACR ≥30 mg/g. RESULTS: The 1-year median testing rate across organizations was 51.6% for both uACR and eGFR, 89.5% for eGFR, and 52.9% for uACR. uACR testing varied (10th–90th percentile) from 44.7 to 63.3% across organizations and from 13.3 to 75.4% across sites. Over 3 years, the median testing rate for uACR across organizations was 73.7%. Overall, the prevalence of detected elevated albuminuria was 15%. The average prevalence of detected elevated albuminuria increased linearly with uACR testing rates at sites, with estimated prevalence of 6%, 15%, and 30% at uACR testing rates of 20%, 50%, and 100%, respectively. CONCLUSIONS: While eGFR testing rates are uniformly high among people with type 2 diabetes, testing rates for uACR are suboptimal and highly variable across and within the organizations examined. Guideline-recommended uACR testing should increase detection of CKD.
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spelling pubmed-87409232022-09-01 Chronic Kidney Disease Testing Among Primary Care Patients With Type 2 Diabetes Across 24 U.S. Health Care Organizations Stempniewicz, Nikita Vassalotti, Joseph A. Cuddeback, John K. Ciemins, Elizabeth Storfer-Isser, Amy Sang, Yingying Matsushita, Kunihiro Ballew, Shoshana H. Chang, Alex R. Levey, Andrew S. Bailey, Robert A. Fishman, Jesse Coresh, Josef Diabetes Care Epidemiology/Health Services Research OBJECTIVE: Clinical guidelines for people with diabetes recommend chronic kidney disease (CKD) testing at least annually using estimated glomerular filtration rate (eGFR) and urinary albumin-to-creatinine ratio (uACR). We aimed to understand CKD testing among people with type 2 diabetes in the U.S. RESEARCH DESIGN AND METHODS: Electronic health record data were analyzed from 513,165 adults with type 2 diabetes receiving primary care from 24 health care organizations and 1,164 clinical practice sites. We assessed the percentage of patients with both one or more eGFRs and one or more uACRs and each test individually in the 1, 2, and 3 years ending September 2019 by health care organization and clinical practice site. Elevated albuminuria was defined as uACR ≥30 mg/g. RESULTS: The 1-year median testing rate across organizations was 51.6% for both uACR and eGFR, 89.5% for eGFR, and 52.9% for uACR. uACR testing varied (10th–90th percentile) from 44.7 to 63.3% across organizations and from 13.3 to 75.4% across sites. Over 3 years, the median testing rate for uACR across organizations was 73.7%. Overall, the prevalence of detected elevated albuminuria was 15%. The average prevalence of detected elevated albuminuria increased linearly with uACR testing rates at sites, with estimated prevalence of 6%, 15%, and 30% at uACR testing rates of 20%, 50%, and 100%, respectively. CONCLUSIONS: While eGFR testing rates are uniformly high among people with type 2 diabetes, testing rates for uACR are suboptimal and highly variable across and within the organizations examined. Guideline-recommended uACR testing should increase detection of CKD. American Diabetes Association 2021-09 2021-07-07 /pmc/articles/PMC8740923/ /pubmed/34233925 http://dx.doi.org/10.2337/dc20-2715 Text en © 2021 by the American Diabetes Association https://www.diabetesjournals.org/content/licenseReaders may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. More information is available at https://www.diabetesjournals.org/content/license.
spellingShingle Epidemiology/Health Services Research
Stempniewicz, Nikita
Vassalotti, Joseph A.
Cuddeback, John K.
Ciemins, Elizabeth
Storfer-Isser, Amy
Sang, Yingying
Matsushita, Kunihiro
Ballew, Shoshana H.
Chang, Alex R.
Levey, Andrew S.
Bailey, Robert A.
Fishman, Jesse
Coresh, Josef
Chronic Kidney Disease Testing Among Primary Care Patients With Type 2 Diabetes Across 24 U.S. Health Care Organizations
title Chronic Kidney Disease Testing Among Primary Care Patients With Type 2 Diabetes Across 24 U.S. Health Care Organizations
title_full Chronic Kidney Disease Testing Among Primary Care Patients With Type 2 Diabetes Across 24 U.S. Health Care Organizations
title_fullStr Chronic Kidney Disease Testing Among Primary Care Patients With Type 2 Diabetes Across 24 U.S. Health Care Organizations
title_full_unstemmed Chronic Kidney Disease Testing Among Primary Care Patients With Type 2 Diabetes Across 24 U.S. Health Care Organizations
title_short Chronic Kidney Disease Testing Among Primary Care Patients With Type 2 Diabetes Across 24 U.S. Health Care Organizations
title_sort chronic kidney disease testing among primary care patients with type 2 diabetes across 24 u.s. health care organizations
topic Epidemiology/Health Services Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740923/
https://www.ncbi.nlm.nih.gov/pubmed/34233925
http://dx.doi.org/10.2337/dc20-2715
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