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Spatially distributed infection increases viral load in a computational model of SARS-CoV-2 lung infection
A key question in SARS-CoV-2 infection is why viral loads and patient outcomes vary dramatically across individuals. Because spatial-temporal dynamics of viral spread and immune response are challenging to study in vivo, we developed Spatial Immune Model of Coronavirus (SIMCoV), a scalable computati...
Autores principales: | Moses, Melanie E., Hofmeyr, Steven, Cannon, Judy L., Andrews, Akil, Gridley, Rebekah, Hinga, Monica, Leyba, Kirtus, Pribisova, Abigail, Surjadidjaja, Vanessa, Tasnim, Humayra, Forrest, Stephanie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740970/ https://www.ncbi.nlm.nih.gov/pubmed/34941862 http://dx.doi.org/10.1371/journal.pcbi.1009735 |
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