Single-cell architecture and functional requirement of alternative splicing during hematopoietic stem cell formation

Single-cell transcriptional profiling has rapidly advanced our understanding of the embryonic hematopoiesis; however, whether and what role RNA alternative splicing (AS) plays remains an enigma. This is important for understanding the mechanisms underlying splicing-associated hematopoietic diseases...

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Detalles Bibliográficos
Autores principales: Wang, Fang, Tan, Puwen, Zhang, Pengcheng, Ren, Yue, Zhou, Jie, Li, Yunqiao, Hou, Siyuan, Li, Shuaili, Zhang, Linlin, Ma, Yanni, Wang, Chaojie, Tang, Wanbo, Wang, Xiaoshuang, Huo, Yue, Hu, Yongfei, Cui, Tianyu, Niu, Chao, Wang, Dong, Liu, Bing, Lan, Yu, Yu, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741192/
https://www.ncbi.nlm.nih.gov/pubmed/34995116
http://dx.doi.org/10.1126/sciadv.abg5369

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