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A second functional furin site in the SARS-CoV-2 spike protein

The ubiquitously-expressed proteolytic enzyme furin is closely related to the pathogenesis of SARS-CoV-2 and therefore represents a key target for antiviral therapy. Based on bioinformatic analysis and pseudovirus tests, we discovered a second functional furin site located in the spike protein. Furi...

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Detalles Bibliográficos
Autores principales:	Zhang, Yue, Zhang, Li, Wu, Jiajing, Yu, Yuanling, Liu, Shuo, Li, Tao, Li, Qianqian, Ding, Ruxia, Wang, Haixin, Nie, Jianhui, Cui, Zhimin, Wang, Yulin, Huang, Weijin, Wang, Youchun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2022
Materias:	Coronaviruses
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741242/ https://www.ncbi.nlm.nih.gov/pubmed/34856891 http://dx.doi.org/10.1080/22221751.2021.2014284

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