Immunomodulation via FGFR inhibition augments FGFR1 targeting T-cell based antitumor immunotherapy for head and neck squamous cell carcinoma

Fibroblast growth factor receptor 1 (FGFR1) is overexpressed in multiple types of solid tumors, including head and neck squamous cell carcinoma (HNSCC). Being associated with poor prognosis, FGFR1 is a potential therapeutic target for aggressive tumors. T cell-based cancer immunotherapy has played a...

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Detalles Bibliográficos
Autores principales: Kono, Michihisa, Komatsuda, Hiroki, Yamaki, Hidekiyo, Kumai, Takumi, Hayashi, Ryusuke, Wakisaka, Risa, Nagato, Toshihiro, Ohkuri, Takayuki, Kosaka, Akemi, Ohara, Kenzo, Kishibe, Kan, Takahara, Miki, Katada, Akihiro, Hayashi, Tatsuya, Kobayashi, Hiroya, Harabuchi, Yasuaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741288/
https://www.ncbi.nlm.nih.gov/pubmed/35003900
http://dx.doi.org/10.1080/2162402X.2021.2021619

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