Cargando…

RNA-Seq Profiling to Investigate the Mechanism of Qishen Granules on Regulating Mitochondrial Energy Metabolism of Heart Failure in Rats

Background. Qishen granules (QSG) are a frequently prescribed formula with cardioprotective properties prescribed to HF for many years. RNA-seq profiling revealed that regulation on cardiac mitochondrial energy metabolism is the main therapeutic effect. However, the underlying mechanism is still unk...

Descripción completa

Detalles Bibliográficos
Autores principales:	He, Hao, Li, Changxiang, Lu, Xiangyu, Li, Yanqin, Li, Xuan, Sun, Xiaoqian, Tang, Binghua, Wu, Yan, Li, Chun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741342/ https://www.ncbi.nlm.nih.gov/pubmed/35003305 http://dx.doi.org/10.1155/2021/5779307

Ejemplares similares

A Network Pharmacology Approach to Explore the Mechanisms of Qishen Granules in Heart Failure
por: Liu, Junjie, et al.
Publicado: (2019)

Qishen granules regulate intestinal microecology to improve cardiac function in rats with heart failure
por: Gao, Kuo, et al.
Publicado: (2023)

The Protective Effect of Qishen Granule on Heart Failure after Myocardial Infarction through Regulation of Calcium Homeostasis
por: Yang, Xiaomin, et al.
Publicado: (2020)

Qishen Granule (QSG) Inhibits Monocytes Released From the Spleen and Protect Myocardial Function via the TLR4-MyD88-NF-κB p65 Pathway in Heart Failure Mice
por: Li, Yanqin, et al.
Publicado: (2022)

P2X7R-NEK7-NLRP3 Inflammasome Activation: A Novel Therapeutic Pathway of Qishen Granule in the Treatment of Acute Myocardial Ischemia
por: Li, Yanqin, et al.
Publicado: (2022)

Antiapoptosis and Antifibrosis Effects of Qishen Granules on Heart Failure Rats via Hippo Pathway
por: Zhang, Jian, et al.
Publicado: (2019)

Safety and efficacy of Qishen granules in patients with chronic heart failure: study protocol for a randomized controlled trial
por: Wang, Jinping, et al.
Publicado: (2017)

Decomposing the Mechanism of Qishen Granules in the Treatment of Heart Failure by a Quantitative Pathway Analysis Method
por: Ren, Weiquan, et al.
Publicado: (2018)

Corrigendum to “Antiapoptosis and Antifibrosis Effects of Qishen Granules on Heart Failure Rats via Hippo Pathway”
por: Zhang, Jian, et al.
Publicado: (2020)

Qishen Granule Improved Cardiac Remodeling via Balancing M1 and M2 Macrophages
por: Lu, Wenji, et al.
Publicado: (2019)

Qishen granules exerts cardioprotective effects on rats with heart failure via regulating fatty acid and glucose metabolism
por: Gao, Kuo, et al.
Publicado: (2020)

Efficacy and safety of Qishen granules for chronic heart failure: A protocol for systematic review and meta-analysis
por: Liu, Junjie, et al.
Publicado: (2020)

The effects of qishen granules for patients with chronic heart failure: A multicenter randomized double-blind placebo-controlled trial
por: Du, Kangjia, et al.
Publicado: (2022)

Qishen Granule Protects against Doxorubicin-Induced Cardiotoxicity by Coordinating MDM2-p53-Mediated Mitophagy and Mitochondrial Biogenesis
por: Li, Weili, et al.
Publicado: (2022)

Qishen granules inhibit myocardial inflammation injury through regulating arachidonic acid metabolism
por: Li, Chun, et al.
Publicado: (2016)

Protective effect of Qishen Yiqi dropping pills on the myocardium of rats with chronic heart failure
por: Lu, Yinghong, et al.
Publicado: (2019)

Efficacy of Qishen Yiqi Drop Pill for Chronic Heart Failure: An Updated Meta-Analysis of 85 Studies
por: Wang, Hao, et al.
Publicado: (2020)

Qishen Yiqi dripping pills for ischemic heart failure: A protocol for a prospective cohort study
por: Zhao, Zhiqiang, et al.
Publicado: (2018)

Qishen Yiqi dripping pills for chronic ischaemic heart failure: results of the CACT‐IHF randomized clinical trial
por: Mao, Jingyuan, et al.
Publicado: (2020)

The role of Qishen Yiqi dripping pills in treating chronic heart failure: An overview of systematic reviews and meta-analyses
por: Chen, Wensheng, et al.
Publicado: (2022)

Efficacy and safety of Qishen Yiqi dripping pills as a complementary treatment for Heart Failure: A protocol of updated systematic review and meta-analysis
por: Guan, Hui, et al.
Publicado: (2021)

Efficacy and Safety of Qishen Yiqi Dripping Pill for Heart Failure With Preserved Ejection Fraction: A Systematic Review and Meta-Analysis
por: Wang, Mengxi, et al.
Publicado: (2021)

Qishen Yiqi Drop Pill improves cardiac function after myocardial ischemia
por: JianXin, Chen, et al.
Publicado: (2016)

The Mechanism Research of Qishen Yiqi Formula by Module-Network Analysis
por: Zheng, Shichao, et al.
Publicado: (2015)

Clinical assessment of complementary treatment with Qishen Yiqi dripping pills on ischemic heart failure: study protocol for a randomized, double-blind, multicenter, placebo-controlled trial (CACT-IHF)
por: Hou, Ya Zhu, et al.
Publicado: (2013)

Immunocytochemical investigation and biochemical function of native matrix granules in the heart mitochondrial matrix
por: Hertsens, R.C., et al.
Publicado: (1987)

Clinical Efficacy and Safety of Qishen Yiqi Dropping Pill Combined with Conventional Western Medicine in the Treatment of Chronic Heart Failure: A Systematic Review and Meta-Analysis
por: Chen, Lisheng, et al.
Publicado: (2021)

Antiplatelet Effects of Qishen Yiqi Dropping Pill in Platelets Aggregation in Hyperlipidemic Rabbits
por: Wang, Yi, et al.
Publicado: (2012)

Qishen Yiqi Dripping Pill Protects Diabetic Nephropathy by Inhibiting the PI3K-AKT Signaling Pathways in Rats
por: Li, Shaohua, et al.
Publicado: (2022)

Integrating scRNA-seq to explore novel macrophage infiltration-associated biomarkers for diagnosis of heart failure
por: Li, Shengnan, et al.
Publicado: (2023)

Qishen capsule safely boosts cardiac function and angiogenesis via the MEK/ERK pathway in a rat myocardial infarction model
por: Guo, Cai-Xia, et al.
Publicado: (2019)

Qishen Yiqi Dropping Pills Ameliorates Doxorubicin-Induced Cardiotoxicity in Mice via Enhancement of Cardiac Angiogenesis
por: Wang, Lijiang, et al.
Publicado: (2019)

Exploring the mechanism of anti-chronic heart failure effect of qiweiqiangxin І granules based on metabolomics
por: Zhong, Wanru, et al.
Publicado: (2023)

Astragalus Granule Prevents Ca(2+) Current Remodeling in Heart Failure by the Downregulation of CaMKII
por: Li, Sinai, et al.
Publicado: (2017)

Qishen Yiqi Drop Pill, a novel compound Chinese traditional medicine protects against high glucose‐induced injury in cardiomyocytes
por: Zhang, Shouyan, et al.
Publicado: (2019)

Hypoxia-induced mitochondrial stress granules
por: Sun, Chun-Ling, et al.
Publicado: (2023)

Macrophage Polarization, Metabolic Reprogramming, and Inflammatory Effects in Ischemic Heart Disease
por: Sun, Xiaoqian, et al.
Publicado: (2022)

Mechanistic Insights of Qingre Jiedu Recipe Based on Network Pharmacology Approach against Heart Failure
por: Li, Xuan, et al.
Publicado: (2022)

Effect of heart failure on catecholamine granule morphology and storage in chromaffin cells
por: Mahata, Sushil K, et al.
Publicado: (2016)

Qishen Yiqi Dripping Pill Protects Against Diabetic Nephropathy by Inhibiting the Wnt/β-Catenin and Transforming Growth Factor-β/Smad Signaling Pathways in Rats
por: Zhang, Qian, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_pq5pne80vd21fc6j979o0fblmu