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Activated but functionally impaired memory Tregs are expanded in slow progressors to type 1 diabetes
AIMS/HYPOTHESIS: Slow progressors to type 1 diabetes are individuals positive for multiple pancreatic islet autoantibodies who have remained diabetes-free for at least 10 years; regulation of the autoimmune response is understudied in this group. Here, we profile CD4(+) regulatory T cells (Tregs) in...
Autores principales: | Boldison, Joanne, Long, Anna E., Aitken, Rachel J., Wilson, Isabel V., Megson, Clare, Hanna, Stephanie J., Wong, F. Susan, Gillespie, Kathleen M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741669/ https://www.ncbi.nlm.nih.gov/pubmed/34709423 http://dx.doi.org/10.1007/s00125-021-05595-0 |
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