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Enhanced glucose metabolism through activation of HIF-1α covers the energy demand in a rat embryonic heart primordium after heartbeat initiation

The initiation of heartbeat is an essential step in cardiogenesis in the heart primordium, but it remains unclear how intracellular metabolism responds to increased energy demands after heartbeat initiation. In this study, embryos in Wistar rats at embryonic day 10, at which heartbeat begins in rats...

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Detalles Bibliográficos
Autores principales: Sato, Tatsuya, Ichise, Nobutoshi, Kobayashi, Takeshi, Fusagawa, Hiroyori, Yamazaki, Hiroya, Kudo, Taiki, Tohse, Noritsugu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741773/
https://www.ncbi.nlm.nih.gov/pubmed/34996938
http://dx.doi.org/10.1038/s41598-021-03832-5