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Enhanced glucose metabolism through activation of HIF-1α covers the energy demand in a rat embryonic heart primordium after heartbeat initiation
The initiation of heartbeat is an essential step in cardiogenesis in the heart primordium, but it remains unclear how intracellular metabolism responds to increased energy demands after heartbeat initiation. In this study, embryos in Wistar rats at embryonic day 10, at which heartbeat begins in rats...
Autores principales: | Sato, Tatsuya, Ichise, Nobutoshi, Kobayashi, Takeshi, Fusagawa, Hiroyori, Yamazaki, Hiroya, Kudo, Taiki, Tohse, Noritsugu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741773/ https://www.ncbi.nlm.nih.gov/pubmed/34996938 http://dx.doi.org/10.1038/s41598-021-03832-5 |
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