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In vitro characterization of a small molecule PD-1 inhibitor that targets the PD-l/PD-L1 interaction

Targeting the programmed cell death protein 1/programmed cell death ligand 1 (PD-1/PD-L1) axis with monoclonal antibodies (mAbs) represents a crucial breakthrough in anticancer therapy, but mAbs are limited by their poor oral bioavailability, adverse events in multiple organ systems, and primary, ad...

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Detalles Bibliográficos
Autores principales:	Lu, Chih-Hao, Chung, Wei-Min, Tsai, Chun-Hao, Cheng, Ju-Chien, Hsu, Kai-Cheng, Tzeng, Huey-En
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741796/ https://www.ncbi.nlm.nih.gov/pubmed/34996924 http://dx.doi.org/10.1038/s41598-021-03590-4

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