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Computational identification of 4-carboxyglutamate sites to supplement physiological studies using deep learning

In biological systems, Glutamic acid is a crucial amino acid which is used in protein biosynthesis. Carboxylation of glutamic acid is a significant post-translational modification which plays important role in blood coagulation by activating prothrombin to thrombin. Contrariwise, 4-carboxy-glutamate...

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Detalles Bibliográficos
Autores principales: Naseer, Sheraz, Ali, Rao Faizan, Fati, Suliman Mohamed, Muneer, Amgad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741832/
https://www.ncbi.nlm.nih.gov/pubmed/34996975
http://dx.doi.org/10.1038/s41598-021-03895-4