Regulation of lung epithelial cell senescence in smoking-induced COPD/emphysema by microR-125a-5p via Sp1 mediation of SIRT1/HIF-1a

Chronic obstructive pulmonary disease (COPD) affects the health of more than 300 million people worldwide; at present, there is no effective drug to treat COPD. Smoking is the most important risk factor, but the molecular mechanism by which smoking causes the disease is unclear. The senescence of lu...

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Detalles Bibliográficos
Autores principales: Wu, Hao, Ma, Huimin, Wang, Lumin, Zhang, Huazhong, Lu, Lu, Xiao, Tian, Cheng, Cheng, Wang, Peiwen, Yang, Yi, Wu, Meng, Wang, Suhua, Zhang, Jinsong, Liu, Qizhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741857/
https://www.ncbi.nlm.nih.gov/pubmed/35002516
http://dx.doi.org/10.7150/ijbs.65861

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