Overview of follicle stimulating hormone and its receptors in reproduction and in stem cells and cancer stem cells

Follicle stimulating hormone (FSH) and its receptor (FSHR) have been reported to be responsible for several physiological functions and cancers. The responsiveness of stem cells and cancer stem cells towards the FSH-FSHR system make the function of FSH and its receptors more interesting in the conte...

Descripción completa

Detalles Bibliográficos
Autores principales: Haldar, Swati, Agrawal, Himanshu, Saha, Sarama, Straughn, Alex R., Roy, Partha, Kakar, Sham S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741861/
https://www.ncbi.nlm.nih.gov/pubmed/35002517
http://dx.doi.org/10.7150/ijbs.63721
_version_ 1784629583150055424
author Haldar, Swati
Agrawal, Himanshu
Saha, Sarama
Straughn, Alex R.
Roy, Partha
Kakar, Sham S.
author_facet Haldar, Swati
Agrawal, Himanshu
Saha, Sarama
Straughn, Alex R.
Roy, Partha
Kakar, Sham S.
author_sort Haldar, Swati
collection PubMed
description Follicle stimulating hormone (FSH) and its receptor (FSHR) have been reported to be responsible for several physiological functions and cancers. The responsiveness of stem cells and cancer stem cells towards the FSH-FSHR system make the function of FSH and its receptors more interesting in the context of cancer biology. This review is comprised of comprehensive information on FSH-FSHR signaling in normal physiology, gonadal stem cells, cancer cells, and potential options of utilizing FSH-FSHR system as an anti-cancer therapeutic target.
format Online
Article
Text
id pubmed-8741861
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Ivyspring International Publisher
record_format MEDLINE/PubMed
spelling pubmed-87418612022-01-08 Overview of follicle stimulating hormone and its receptors in reproduction and in stem cells and cancer stem cells Haldar, Swati Agrawal, Himanshu Saha, Sarama Straughn, Alex R. Roy, Partha Kakar, Sham S. Int J Biol Sci Review Follicle stimulating hormone (FSH) and its receptor (FSHR) have been reported to be responsible for several physiological functions and cancers. The responsiveness of stem cells and cancer stem cells towards the FSH-FSHR system make the function of FSH and its receptors more interesting in the context of cancer biology. This review is comprised of comprehensive information on FSH-FSHR signaling in normal physiology, gonadal stem cells, cancer cells, and potential options of utilizing FSH-FSHR system as an anti-cancer therapeutic target. Ivyspring International Publisher 2022-01-01 /pmc/articles/PMC8741861/ /pubmed/35002517 http://dx.doi.org/10.7150/ijbs.63721 Text en © The author(s) https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/). See http://ivyspring.com/terms for full terms and conditions.
spellingShingle Review
Haldar, Swati
Agrawal, Himanshu
Saha, Sarama
Straughn, Alex R.
Roy, Partha
Kakar, Sham S.
Overview of follicle stimulating hormone and its receptors in reproduction and in stem cells and cancer stem cells
title Overview of follicle stimulating hormone and its receptors in reproduction and in stem cells and cancer stem cells
title_full Overview of follicle stimulating hormone and its receptors in reproduction and in stem cells and cancer stem cells
title_fullStr Overview of follicle stimulating hormone and its receptors in reproduction and in stem cells and cancer stem cells
title_full_unstemmed Overview of follicle stimulating hormone and its receptors in reproduction and in stem cells and cancer stem cells
title_short Overview of follicle stimulating hormone and its receptors in reproduction and in stem cells and cancer stem cells
title_sort overview of follicle stimulating hormone and its receptors in reproduction and in stem cells and cancer stem cells
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741861/
https://www.ncbi.nlm.nih.gov/pubmed/35002517
http://dx.doi.org/10.7150/ijbs.63721
work_keys_str_mv AT haldarswati overviewoffolliclestimulatinghormoneanditsreceptorsinreproductionandinstemcellsandcancerstemcells
AT agrawalhimanshu overviewoffolliclestimulatinghormoneanditsreceptorsinreproductionandinstemcellsandcancerstemcells
AT sahasarama overviewoffolliclestimulatinghormoneanditsreceptorsinreproductionandinstemcellsandcancerstemcells
AT straughnalexr overviewoffolliclestimulatinghormoneanditsreceptorsinreproductionandinstemcellsandcancerstemcells
AT roypartha overviewoffolliclestimulatinghormoneanditsreceptorsinreproductionandinstemcellsandcancerstemcells
AT kakarshams overviewoffolliclestimulatinghormoneanditsreceptorsinreproductionandinstemcellsandcancerstemcells

Ejemplares similares