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Comprehensive quantitative analysis of alternative splicing variants reveals the HNF1B mRNA splicing pattern in various tumour and non-tumour tissues

Hepatocyte nuclear factor-1-beta (HNF1B) is a transcription factor and putative biomarker of solid tumours. Recently, we have revealed a variety of HNF1B mRNA alternative splicing variants (ASVs) with unknown, but potentially regulatory, functions. The aim of our work was to quantify the most common...

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Detalles Bibliográficos
Autores principales: Hojny, Jan, Michalkova, Romana, Krkavcova, Eva, Bui, Quang Hiep, Bartu, Michaela, Nemejcova, Kristyna, Kalousova, Marta, Kleiblova, Petra, Dundr, Pavel, Struzinska, Ivana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741901/
https://www.ncbi.nlm.nih.gov/pubmed/34997048
http://dx.doi.org/10.1038/s41598-021-03989-z