Ablation of VLA4 in multiple myeloma cells redirects tumor spread and prolongs survival

Multiple myeloma (MM) is a cancer of bone marrow (BM) plasma cells, which is increasingly treatable but still incurable. In 90% of MM patients, severe osteolysis results from pathological interactions between MM cells and the bone microenvironment. Delineating specific molecules and pathways for the...

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Detalles Bibliográficos
Autores principales: Hathi, Deep, Chanswangphuwana, Chantiya, Cho, Nicholas, Fontana, Francesca, Maji, Dolonchampa, Ritchey, Julie, O’Neal, Julie, Ghai, Anchal, Duncan, Kathleen, Akers, Walter J., Fiala, Mark, Vij, Ravi, DiPersio, John F., Rettig, Michael, Shokeen, Monica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741970/
https://www.ncbi.nlm.nih.gov/pubmed/34996933
http://dx.doi.org/10.1038/s41598-021-03748-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741970/
https://www.ncbi.nlm.nih.gov/pubmed/34996933
http://dx.doi.org/10.1038/s41598-021-03748-0

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