Cargando…

Single-cell transcriptomics defines keratinocyte differentiation in avian scutate scales

The growth of skin appendages, such as hair, feathers and scales, depends on terminal differentiation of epidermal keratinocytes. Here, we investigated keratinocyte differentiation in avian scutate scales. Cells were isolated from the skin on the legs of 1-day old chicks and subjected to single-cell...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lachner, Julia, Ehrlich, Florian, Wielscher, Matthias, Farlik, Matthias, Hermann, Marcela, Tschachler, Erwin, Eckhart, Leopold
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742010/ https://www.ncbi.nlm.nih.gov/pubmed/34997067 http://dx.doi.org/10.1038/s41598-021-04082-1

Ejemplares similares

Convergent Evolution of Cysteine-Rich Keratins in Hard Skin Appendages of Terrestrial Vertebrates
por: Ehrlich, Florian, et al.
Publicado: (2020)

Epidermal cornification is preceded by the expression of a keratinocyte-specific set of pyroptosis-related genes
por: Lachner, Julia, et al.
Publicado: (2017)

TINCR is not a non‐coding RNA but encodes a protein component of cornified epidermal keratinocytes
por: Eckhart, Leopold, et al.
Publicado: (2020)

Immunolocalization and phylogenetic profiling of the feather protein with the highest cysteine content
por: Lachner, Julia, et al.
Publicado: (2019)

The Trichohyalin-Like Protein Scaffoldin Is Expressed in the Multilayered Periderm during Development of Avian Beak and Egg Tooth
por: Mlitz, Veronika, et al.
Publicado: (2021)

A Stress Response Program at the Origin of Evolutionary Innovation in the Skin
por: Eckhart, Leopold, et al.
Publicado: (2019)

Gene duplications and gene loss in the epidermal differentiation complex during the evolutionary land-to-water transition of cetaceans
por: Holthaus, Karin Brigit, et al.
Publicado: (2021)

Comparative Analysis of Epidermal Differentiation Genes of Crocodilians Suggests New Models for the Evolutionary Origin of Avian Feather Proteins
por: Holthaus, Karin Brigit, et al.
Publicado: (2018)

Comprehensive molecular and cellular studies suggest avian scutate scales are secondarily derived from feathers, and more distant from reptilian scales
por: Wu, Ping, et al.
Publicado: (2018)

Inactivation of DNase1L2 and DNase2 in keratinocytes suppresses DNA degradation during epidermal cornification and results in constitutive parakeratosis
por: Fischer, Heinz, et al.
Publicado: (2017)

Convergent evolution of cysteine-rich proteins in feathers and hair
por: Strasser, Bettina, et al.
Publicado: (2015)

‘Don't be so over-protective!’
por: Tschachler, Erwin, et al.
Publicado: (2012)

Autophagic Control of Skin Aging
por: Eckhart, Leopold, et al.
Publicado: (2019)

Inactivation of Autophagy in Keratinocytes Reduces Tumor Growth in Mouse Models of Epithelial Skin Cancer
por: Barresi, Caterina, et al.
Publicado: (2022)

Identification of Chicken Transglutaminase 1 and In Situ Localization of Transglutaminase Activity in Avian Skin and Esophagus
por: Sachslehner, Attila Placido, et al.
Publicado: (2021)

Comparative genomics suggests loss of keratin K24 in three evolutionary lineages of mammals
por: Ehrlich, Florian, et al.
Publicado: (2019)

Immunolocalization of a Histidine-Rich Epidermal Differentiation Protein in the Chicken Supports the Hypothesis of an Evolutionary Developmental Link between the Embryonic Subperiderm and Feather Barbs and Barbules
por: Alibardi, Lorenzo, et al.
Publicado: (2016)

Cytosolic DNA sensing through cGAS and STING is inactivated by gene mutations in pangolins
por: Fischer, Heinz, et al.
Publicado: (2020)

Pangolins Lack IFIH1/MDA5, a Cytoplasmic RNA Sensor That Initiates Innate Immune Defense Upon Coronavirus Infection
por: Fischer, Heinz, et al.
Publicado: (2020)

Heme Oxygenase-1 Is Upregulated during Differentiation of Keratinocytes but Its Expression Is Dispensable for Cornification of Murine Epidermis
por: Surbek, Marta, et al.
Publicado: (2023)

Cornification of nail keratinocytes requires autophagy for bulk degradation of intracellular proteins while sparing components of the cytoskeleton
por: Jaeger, Karin, et al.
Publicado: (2018)

NOD2 and reproduction-associated NOD-like receptors have been lost during the evolution of pangolins
por: Salova, Margarita, et al.
Publicado: (2021)

Identification of epidermal differentiation genes of the tuatara provides insights into the early evolution of lepidosaurian skin
por: Holthaus, Karin Brigit, et al.
Publicado: (2020)

Evolutionary Origin and Diversification of Epidermal Barrier Proteins in Amniotes
por: Strasser, Bettina, et al.
Publicado: (2014)

Comparative genomics reveals conservation of filaggrin and loss of caspase-14 in dolphins
por: Strasser, Bettina, et al.
Publicado: (2015)

Differential Evolution of the Epidermal Keratin Cytoskeleton in Terrestrial and Aquatic Mammals
por: Ehrlich, Florian, et al.
Publicado: (2019)

In situ labeling of DNA reveals interindividual variation in nuclear DNA breakdown in hair and may be useful to predict success of forensic genotyping of hair
por: Szabo, Sandra, et al.
Publicado: (2011)

The Expression of the Endogenous mTORC1 Inhibitor Sestrin 2 Is Induced by UVB and Balanced with the Expression Level of Sestrin 1
por: Mlitz, Veronika, et al.
Publicado: (2016)

Identification and comparative analysis of the epidermal differentiation complex in snakes
por: Brigit Holthaus, Karin, et al.
Publicado: (2017)

Double deficiency of Trex2 and DNase1L2 nucleases leads to accumulation of DNA in lingual cornifying keratinocytes without activating inflammatory responses
por: Manils, Joan, et al.
Publicado: (2017)

DNase 2 Is the Main DNA-Degrading Enzyme of the Stratum Corneum
por: Fischer, Heinz, et al.
Publicado: (2011)

Histamine suppresses epidermal keratinocyte differentiation and impairs skin barrier function in a human skin model
por: Gschwandtner, M, et al.
Publicado: (2013)

Autophagy in the Thymic Epithelium Is Dispensable for the Development of Self-Tolerance in a Novel Mouse Model
por: Sukseree, Supawadee, et al.
Publicado: (2012)

Identification of Genetic Risk Factors for Keratinocyte Cancer in Immunosuppressed Solid Organ Transplant Recipients: A Case-Control Study
por: Sunder-Plassmann, Raute, et al.
Publicado: (2023)

The transcriptional profile of keloidal Schwann cells
por: Direder, Martin, et al.
Publicado: (2022)

Autophagy deficient keratinocytes display increased DNA damage, senescence and aberrant lipid composition after oxidative stress in vitro and in vivo
por: Song, Xiuzu, et al.
Publicado: (2016)

Establishment of keratinocyte cell lines from human hair follicles
por: Wagner, Tanja, et al.
Publicado: (2018)

Comparative Genomics Identifies Epidermal Proteins Associated with the Evolution of the Turtle Shell
por: Holthaus, Karin Brigit, et al.
Publicado: (2016)

Activation of Nrf2 in keratinocytes causes chloracne (MADISH)-like skin disease in mice
por: Schäfer, Matthias, et al.
Publicado: (2014)

miR-155 Contributes to Normal Keratinocyte Differentiation and Is Upregulated in the Epidermis of Psoriatic Skin Lesions
por: Beer, Lucian, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_h4ngu7jmmi1j7rnjb88qgbl9nn