High cell surface expression and peptide binding affinity of HLA-DQA1*05:03, a susceptible allele of neuromyelitis optica spectrum disorders (NMOSD)

Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease characterized by the presence of pathogenic autoantibodies, anti-aquaporin 4 (AQP4) antibodies. Recently, HLA-DQA1*05:03 was shown to be significantly associated with NMOSD in a Japanese patient cohort. However, the spe...

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Detalles Bibliográficos
Autores principales: Beppu, Shohei, Kinoshita, Makoto, Wilamowski, Jan, Suenaga, Tadahiro, Yasumizu, Yoshiaki, Ogawa, Kotaro, Ishikura, Teruyuki, Tada, Satoru, Koda, Toru, Murata, Hisashi, Shiraishi, Naoyuki, Sugiyama, Yasuko, Kihara, Keigo, Sugimoto, Tomoyuki, Arase, Hisashi, Standley, Daron M., Okuno, Tatsusada, Mochizuki, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742014/
https://www.ncbi.nlm.nih.gov/pubmed/34997058
http://dx.doi.org/10.1038/s41598-021-04074-1

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