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PEA-15 engages in allosteric interactions using a common scaffold in a phosphorylation-dependent manner

Phosphoprotein enriched in astrocytes, 15 kDa (PEA-15) is a death-effector domain (DED) containing protein involved in regulating mitogen-activated protein kinase and apoptosis pathways. In this molecular dynamics study, we examined how phosphorylation of the PEA-15 C-terminal tail residues, Ser-104...

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Detalles Bibliográficos
Autores principales:	Ikedife, Joyce, He, Jianlin, Wei, Yufeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742051/ https://www.ncbi.nlm.nih.gov/pubmed/34997083 http://dx.doi.org/10.1038/s41598-021-04099-6

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