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Cholinergic anti-inflammatory pathway ameliorates murine experimental Th2-type colitis by suppressing the migration of plasmacytoid dendritic cells

Ulcerative colitis (UC) is a chronic inflammatory bowel disease. Several studies have demonstrated that α7 nicotinic acetylcholine receptors (α7nAChRs) exert anti-inflammatory effects on immune cells and nicotine suppress UC onset and relapse. Plasmacytoid dendritic cells (pDCs) reportedly accumulat...

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Detalles Bibliográficos
Autores principales: Kanauchi, Yuya, Yamamoto, Takeshi, Yoshida, Minako, Zhang, Yue, Lee, Jaemin, Hayashi, Shusaku, Kadowaki, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742068/
https://www.ncbi.nlm.nih.gov/pubmed/34997096
http://dx.doi.org/10.1038/s41598-021-04154-2

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