Osteonecrosis development by tooth extraction in zoledronate treated mice is inhibited by active vitamin D analogues, anti-inflammatory agents or antibiotics

Invasive dental treatment such as tooth extraction following treatment with strong anti-bone resorptive agents, including bisphosphonates and denosumab, reportedly promotes osteonecrosis of the jaw (ONJ) at the extraction site, but strategies to prevent ONJ remain unclear. Here we show that in mice,...

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Detalles Bibliográficos
Autores principales: Soma, Tomoya, Iwasaki, Ryotaro, Sato, Yuiko, Kobayashi, Tami, Ito, Eri, Matsumoto, Tatsuaki, Kimura, Atsushi, Miyamoto, Kana, Matsumoto, Morio, Nakamura, Masaya, Morita, Mayu, Asoda, Seiji, Kawana, Hiromasa, Nakagawa, Taneaki, Miyamoto, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742126/
https://www.ncbi.nlm.nih.gov/pubmed/34997043
http://dx.doi.org/10.1038/s41598-021-03966-6

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