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Epac‐2 ameliorates spontaneous colitis in Il‐10 (−/−) mice by protecting the intestinal barrier and suppressing NF‐κB/MAPK signalling

Intestinal barrier dysfunction and intestinal inflammation interact in the progression of Crohn's disease (CD). A recent study indicated that Epac‐2 protected the intestinal barrier and had anti‐inflammatory effects. The present study examined the function of Epac‐2 in CD‐like colitis. Interleu...

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Detalles Bibliográficos
Autores principales:	Song, Xue, Wen, Hexin, Zuo, Lugen, Geng, Zhijun, Nian, Jing, Wang, Luyao, Jiang, Yifan, Tao, Jing, Zhu, Zihan, Wu, Xiaopei, Wang, Zhikun, Zhang, Xiaofeng, Yu, Liang, Zhao, Hao, Xiang, Ping, Li, Jing, Shen, Lin, Hu, Jianguo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742196/ https://www.ncbi.nlm.nih.gov/pubmed/34862717 http://dx.doi.org/10.1111/jcmm.17077

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