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The Generalized Robinson-Foulds Distance for Phylogenetic Trees

The Robinson-Foulds (RF) distance, one of the most widely used metrics for comparing phylogenetic trees, has the advantage of being intuitive, with a natural interpretation in terms of common splits, and it can be computed in linear time, but it has a very low resolution, and it may become trivial f...

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Detalles Bibliográficos
Autores principales: Llabrés, Mercè, Rosselló, Francesc, Valiente, Gabriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742253/
https://www.ncbi.nlm.nih.gov/pubmed/34714118
http://dx.doi.org/10.1089/cmb.2021.0342
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author Llabrés, Mercè
Rosselló, Francesc
Valiente, Gabriel
author_facet Llabrés, Mercè
Rosselló, Francesc
Valiente, Gabriel
author_sort Llabrés, Mercè
collection PubMed
description The Robinson-Foulds (RF) distance, one of the most widely used metrics for comparing phylogenetic trees, has the advantage of being intuitive, with a natural interpretation in terms of common splits, and it can be computed in linear time, but it has a very low resolution, and it may become trivial for phylogenetic trees with overlapping taxa, that is, phylogenetic trees that share some but not all of their leaf labels. In this article, we study the properties of the Generalized Robinson-Foulds (GRF) distance, a recently proposed metric for comparing any structures that can be described by multisets of multisets of labels, when applied to rooted phylogenetic trees with overlapping taxa, which are described by sets of clusters, that is, by sets of sets of labels. We show that the GRF distance has a very high resolution, it can also be computed in linear time, and it is not (uniformly) equivalent to the RF distance.
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spelling pubmed-87422532022-01-10 The Generalized Robinson-Foulds Distance for Phylogenetic Trees Llabrés, Mercè Rosselló, Francesc Valiente, Gabriel J Comput Biol Research Articles The Robinson-Foulds (RF) distance, one of the most widely used metrics for comparing phylogenetic trees, has the advantage of being intuitive, with a natural interpretation in terms of common splits, and it can be computed in linear time, but it has a very low resolution, and it may become trivial for phylogenetic trees with overlapping taxa, that is, phylogenetic trees that share some but not all of their leaf labels. In this article, we study the properties of the Generalized Robinson-Foulds (GRF) distance, a recently proposed metric for comparing any structures that can be described by multisets of multisets of labels, when applied to rooted phylogenetic trees with overlapping taxa, which are described by sets of clusters, that is, by sets of sets of labels. We show that the GRF distance has a very high resolution, it can also be computed in linear time, and it is not (uniformly) equivalent to the RF distance. Mary Ann Liebert, Inc., publishers 2021-12-01 2021-12-10 /pmc/articles/PMC8742253/ /pubmed/34714118 http://dx.doi.org/10.1089/cmb.2021.0342 Text en © Mercè Llabrés, et al., 2021. Published by Mary Ann Liebert, Inc. https://creativecommons.org/licenses/by-nc/4.0/This Open Access article is distributed under the terms of the Creative Commons Attribution Noncommercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.
spellingShingle Research Articles
Llabrés, Mercè
Rosselló, Francesc
Valiente, Gabriel
The Generalized Robinson-Foulds Distance for Phylogenetic Trees
title The Generalized Robinson-Foulds Distance for Phylogenetic Trees
title_full The Generalized Robinson-Foulds Distance for Phylogenetic Trees
title_fullStr The Generalized Robinson-Foulds Distance for Phylogenetic Trees
title_full_unstemmed The Generalized Robinson-Foulds Distance for Phylogenetic Trees
title_short The Generalized Robinson-Foulds Distance for Phylogenetic Trees
title_sort generalized robinson-foulds distance for phylogenetic trees
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742253/
https://www.ncbi.nlm.nih.gov/pubmed/34714118
http://dx.doi.org/10.1089/cmb.2021.0342
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