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Administration of High-Dose Methylprednisolone Worsens Bone Loss after Acute Spinal Cord Injury in Rats

The administration of high-dose methylprednisolone (MP) for 24–48 h after traumatic spinal cord injury (SCI) has been shown to improve functional recovery. The known adverse effects of MP on skeletal muscle and the immune system, though, have raised clinically relevant safety concerns. However, the...

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Detalles Bibliográficos
Autores principales: Peng, Yuanzhen, Zhao, Wei, Hu, Yizhong, Guo, X. Edward, Wang, Jun, Hao, Ke, He, Zhiming, Toro, Carlos, Bauman, William A., Qin, Weiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742306/
https://www.ncbi.nlm.nih.gov/pubmed/35018361
http://dx.doi.org/10.1089/neur.2021.0035