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Epigenetic regulation of 5α reductase-1 underlies adaptive plasticity of reproductive function and pubertal timing
BACKGROUND: Women facing increased energetic demands in childhood commonly have altered adult ovarian activity and shorter reproductive lifespan, possibly comprising a strategy to optimize reproductive success. Here, we sought to understand the mechanisms of early-life programming of reproductive fu...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742331/ https://www.ncbi.nlm.nih.gov/pubmed/34996447 http://dx.doi.org/10.1186/s12915-021-01219-6 |