Restriction of extracellular lipids renders pancreatic cancer dependent on autophagy

BACKGROUND: KRAS is the predominant oncogene mutated in pancreatic ductal adenocarcinoma (PDAC), the fourth cause of cancer-related deaths worldwide. Mutant KRAS-driven tumors are metabolically programmed to support their growth and survival, which can be used to identify metabolic vulnerabilities....

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Detalles Bibliográficos
Autores principales: Saliakoura, Maria, Sebastiano, Matteo Rossi, Nikdima, Ioanna, Pozzato, Chiara, Konstantinidou, Georgia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742413/
https://www.ncbi.nlm.nih.gov/pubmed/34998392
http://dx.doi.org/10.1186/s13046-021-02231-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742413/
https://www.ncbi.nlm.nih.gov/pubmed/34998392
http://dx.doi.org/10.1186/s13046-021-02231-y

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