Cargando…

Adipocyte-specific deletion of PIP5K1c reduces diet-induced obesity and insulin resistance by increasing energy expenditure

BACKGROUND: Phosphatidylinositol 4-phosphate 5-kinase type I c (PIP5K1c) catalyses the synthesis of phospholipid phosphatidylinositol 4,5-bisphosphate (PIP2) by phosphorylating phosphatidylinositol 4 phosphate, which plays multiple roles in regulating focal adhesion formation, invasion, and cell mig...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Guan, Yang, Cuishan, Guo, Sheng, Huang, Miaoling, Deng, Liping, Huang, Ying, Chen, Puxin, Chen, Feng, Huang, Xiaohong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742433/ https://www.ncbi.nlm.nih.gov/pubmed/34996482 http://dx.doi.org/10.1186/s12944-021-01616-4

Ejemplares similares

PIP(2) PIP(2) Hooray for Maxi K(+)
por: Rittenhouse, Ann R.
Publicado: (2008)

Adipocyte-specific Nos2 deletion improves insulin resistance and dyslipidemia through brown fat activation in diet-induced obese mice
por: Vilela, Vanessa Rodrigues, et al.
Publicado: (2022)

Conditional deletion of Pip5k1c in sensory ganglia and effects on nociception and inflammatory sensitization
por: Loo, Lipin, et al.
Publicado: (2017)

Grail is involved in adipocyte differentiation and diet-induced obesity
por: Liu, Peiyao, et al.
Publicado: (2018)

AKAP1 Deficiency Attenuates Diet‐Induced Obesity and Insulin Resistance by Promoting Fatty Acid Oxidation and Thermogenesis in Brown Adipocytes
por: Ji, Lele, et al.
Publicado: (2021)

Fibroblast Growth Factor 21 Reverses Hepatic Steatosis, Increases Energy Expenditure, and Improves Insulin Sensitivity in Diet-Induced Obese Mice
por: Xu, Jing, et al.
Publicado: (2009)

Myeloperoxidase Deletion Prevents High-Fat Diet–Induced Obesity and Insulin Resistance
por: Wang, Qilong, et al.
Publicado: (2014)

Lipid kinases PIP5K7 and PIP5K9 are required for polyamine‐triggered K(+) efflux in Arabidopsis roots
por: Zarza, Xavier, et al.
Publicado: (2020)

Helminthostachys zeylanica alleviates hepatic steatosis and insulin resistance in diet-induced obese mice
por: Chang, Ting-Chen, et al.
Publicado: (2019)

Diet, Obesity, and Cancer Progression: Are Adipocytes the Link?
por: Toren, Paul, et al.
Publicado: (2013)

Adipocyte-specific CD1d-deficiency mitigates diet-induced obesity and insulin resistance in mice
por: Satoh, Masashi, et al.
Publicado: (2016)

Astragaloside IV Regulates Insulin Resistance and Inflammatory Response of Adipocytes via Modulating CTRP3 and PI3K/AKT Signaling
por: Zhang, Yue, et al.
Publicado: (2022)

Apoptotic brown adipocytes enhance energy expenditure via extracellular inosine
por: Niemann, Birte, et al.
Publicado: (2022)

X1AKAP1 Deficiency Attenuates Diet‐Induced Obesity and Insulin Resistance by Promoting Fatty Acid Oxidation and Thermogenesis in Brown Adipocytes
por: Ji, Lele, et al.
Publicado: (2022)

Akt phosphorylates insulin receptor substrate to limit PI3K-mediated PIP3 synthesis
por: Kearney, Alison L, et al.
Publicado: (2021)

Suppression of obesity by melatonin through increasing energy expenditure and accelerating lipolysis in mice fed a high-fat diet
por: Xu, Liang, et al.
Publicado: (2022)

Intraperitoneal administration of follistatin promotes adipocyte browning in high-fat diet-induced obese mice
por: Li, Haoyu, et al.
Publicado: (2019)

Deletion of adipocyte prohibitin 1 exacerbates high‐fat diet‐induced steatosis but not liver inflammation and fibrosis
por: Wang, Xiaolin, et al.
Publicado: (2022)

Phytohemagglutinin ameliorates HFD-induced obesity by increasing energy expenditure
por: Zhang, Yunxia, et al.
Publicado: (2021)

Bmp8a deletion leads to obesity through regulation of lipid metabolism and adipocyte differentiation
por: Zhong, Shenjie, et al.
Publicado: (2023)

Dexamethasone Reduces Energy Expenditure And Increases Susceptibility To Diet-Induced Obesity In Mice
por: Poggioli, Raffaella, et al.
Publicado: (2013)

Does diet and activity lead to difference in resting energy expenditure in obese women?
por: Masoumi, Zahra Taghadomi, et al.
Publicado: (2023)

Adipocyte-Specific Deletion of Manganese Superoxide Dismutase Protects From Diet-Induced Obesity Through Increased Mitochondrial Uncoupling and Biogenesis
por: Han, Yong Hwan, et al.
Publicado: (2016)

Adipocyte OGT governs diet-induced hyperphagia and obesity
por: Li, Min-Dian, et al.
Publicado: (2018)

Reprogrammed Functional Brown Adipocytes Ameliorate Insulin Resistance and Dyslipidemia in Diet-Induced Obesity and Type 2 Diabetes
por: Kishida, Tsunao, et al.
Publicado: (2015)

Mice with a Targeted Deletion of the Type 2 Deiodinase Are Insulin Resistant and Susceptible to Diet Induced Obesity
por: Marsili, Alessandro, et al.
Publicado: (2011)

Correction: Intraperitoneal administration of follistatin promotes adipocyte browning in high-fat diet-induced obese mice
por: Li, Haoyu, et al.
Publicado: (2019)

Deletion of Trim28 in committed adipocytes promotes obesity but preserves glucose tolerance
por: Bond, Simon T., et al.
Publicado: (2021)

Little PIP, little PIP, let me in
por: LeBrasseur, Nicole
Publicado: (2002)

β-Adrenoceptor Signaling Networks in Adipocytes for Recruiting Stored Fat and Energy Expenditure
por: Collins, Sheila
Publicado: (2012)

The Role of Nrf2: Adipocyte Differentiation, Obesity, and Insulin Resistance
por: Seo, Hyun-Ae, et al.
Publicado: (2013)

Obesity Resistance and Enhanced Insulin Sensitivity in Ahnak (-/-) Mice Fed a High Fat Diet Are Related to Impaired Adipogenesis and Increased Energy Expenditure
por: Shin, Jae Hoon, et al.
Publicado: (2015)

Truncation of Pik3r1 causes severe insulin resistance uncoupled from obesity and dyslipidaemia by increased energy expenditure
por: Kwok, Albert, et al.
Publicado: (2020)

T reg–specific insulin receptor deletion prevents diet-induced and age-associated metabolic syndrome
por: Wu, Dan, et al.
Publicado: (2020)

Activation of the adipocyte CREB/CRTC pathway in obesity
por: Yoon, Young-Sil, et al.
Publicado: (2021)

Hormone-induced mitochondrial fission is utilized by brown adipocytes as an amplification pathway for energy expenditure
por: Wikstrom, Jakob D, et al.
Publicado: (2014)

Energy expenditure and body composition changes after an isocaloric ketogenic diet in overweight and obese men: A secondary analysis of energy expenditure and physical activity
por: Friedman, Mark I., et al.
Publicado: (2019)

Correction: Obesity Resistance and Enhanced Insulin Sensitivity in Ahnak (-/-) Mice Fed a High Fat Diet Are Related to Impaired Adipogenesis and Increased Energy Expenditure
por: Shin, Jae Hoon, et al.
Publicado: (2015)

Phospholipid Scramblase 4 (PLSCR4) Regulates Adipocyte Differentiation via PIP3-Mediated AKT Activation
por: Barth, Lisa A. G., et al.
Publicado: (2022)

Directing visceral white adipocyte precursors to a thermogenic adipocyte fate improves insulin sensitivity in obese mice
por: Hepler, Chelsea, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_tnksjqji1l19l1fethmr9fj5e4