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METTL3 promotes lung adenocarcinoma tumor growth and inhibits ferroptosis by stabilizing SLC7A11 m(6)A modification

BACKGROUND: N6-methyladenosine (m(6)A) has emerged as a significant regulator of the progress of various cancers. However, its role in lung adenocarcinoma (LUAD) remains unclear. Here, we explored the biological function and underlying mechanism of methyltransferase-like 3 (METTL3), the main catalys...

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Detalles Bibliográficos
Autores principales:	Xu, Yiming, Lv, Dandan, Yan, Chao, Su, Hua, Zhang, Xue, Shi, Yangfeng, Ying, Kejing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742440/ https://www.ncbi.nlm.nih.gov/pubmed/34996469 http://dx.doi.org/10.1186/s12935-021-02433-6

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