Therapeutical interference with the epigenetic landscape of germ cell tumors: a comparative drug study and new mechanistical insights

BACKGROUND: Type II germ cell tumors (GCT) are the most common solid cancers in males of age 15 to 35 years. Treatment of these tumors includes cisplatin-based therapy achieving high cure rates, but also leading to late toxicities. As mainly young men are suffering from GCTs, late toxicities play a...

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Detalles Bibliográficos
Autores principales: Müller, Melanie R., Burmeister, Aaron, Skowron, Margaretha A., Stephan, Alexa, Bremmer, Felix, Wakileh, Gamal A., Petzsch, Patrick, Köhrer, Karl, Albers, Peter, Nettersheim, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742467/
https://www.ncbi.nlm.nih.gov/pubmed/34996497
http://dx.doi.org/10.1186/s13148-021-01223-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742467/
https://www.ncbi.nlm.nih.gov/pubmed/34996497
http://dx.doi.org/10.1186/s13148-021-01223-1

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