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Dual energy CT in necrotizing enterocolitis; a novel diagnostic approach

BACKGROUND/AIM: Necrotizing enterocolitis (NEC) is one of the most important causes of morbidity and mortality in premature infants. Although there are no specific diagnostic tools, the main factors affecting prognosis are clinical and laboratory findings, and early diagnosis and treatment. In this...

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Autores principales: ÇAĞLAR, Özgür, CESUR, Emrullah, SADE, Recep, FIRINCI, Binali, KARA, Mustafa, ÇELİKKAYA, Mehmet Emin, ORAL, Akgün, YİĞİTER, Murat, ÖZMEN, Sevilay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Scientific and Technological Research Council of Turkey 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742483/
https://www.ncbi.nlm.nih.gov/pubmed/34333905
http://dx.doi.org/10.3906/sag-2103-294
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author ÇAĞLAR, Özgür
CESUR, Emrullah
SADE, Recep
FIRINCI, Binali
KARA, Mustafa
ÇELİKKAYA, Mehmet Emin
ORAL, Akgün
YİĞİTER, Murat
ÖZMEN, Sevilay
author_facet ÇAĞLAR, Özgür
CESUR, Emrullah
SADE, Recep
FIRINCI, Binali
KARA, Mustafa
ÇELİKKAYA, Mehmet Emin
ORAL, Akgün
YİĞİTER, Murat
ÖZMEN, Sevilay
author_sort ÇAĞLAR, Özgür
collection PubMed
description BACKGROUND/AIM: Necrotizing enterocolitis (NEC) is one of the most important causes of morbidity and mortality in premature infants. Although there are no specific diagnostic tools, the main factors affecting prognosis are clinical and laboratory findings, and early diagnosis and treatment. In this study, we demonstrate the importance of dual-energy computed tomography (DECT) in confirming intestinal ischemia in neonates with NEC. MATERIALS AND METHODS: Patients diagnosed with NEC in a neonatal intensive care unit were staged according to modified Bell’s classification, and DECT was performed on patients with NEC stages 2-A, 2-B and 3-A. According to their DECT reports, these patients were then separated into two groups: those with intestinal ischemia and those without intestinal ischemia. The patients with intestinal ischemia were evaluated using surgical reports, and the other patients were evaluated using clinical findings. RESULTS: DECT was performed in 21 patients with NEC stages 2-A, 2-B and 3-A. Twelve patients (57.1%) without ischemia were followed up without surgery. Nine patients (42.9%) with ischemia on DECT were operated on, and resection and anastomosis or ileostomy and colostomy were performed. CONCLUSION: In patients with NEC, DECT significantly increases overall diagnostic confidence in assessing intestinal necrosis when compared with traditional diagnostic methods.
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spelling pubmed-87424832022-01-20 Dual energy CT in necrotizing enterocolitis; a novel diagnostic approach ÇAĞLAR, Özgür CESUR, Emrullah SADE, Recep FIRINCI, Binali KARA, Mustafa ÇELİKKAYA, Mehmet Emin ORAL, Akgün YİĞİTER, Murat ÖZMEN, Sevilay Turk J Med Sci Article BACKGROUND/AIM: Necrotizing enterocolitis (NEC) is one of the most important causes of morbidity and mortality in premature infants. Although there are no specific diagnostic tools, the main factors affecting prognosis are clinical and laboratory findings, and early diagnosis and treatment. In this study, we demonstrate the importance of dual-energy computed tomography (DECT) in confirming intestinal ischemia in neonates with NEC. MATERIALS AND METHODS: Patients diagnosed with NEC in a neonatal intensive care unit were staged according to modified Bell’s classification, and DECT was performed on patients with NEC stages 2-A, 2-B and 3-A. According to their DECT reports, these patients were then separated into two groups: those with intestinal ischemia and those without intestinal ischemia. The patients with intestinal ischemia were evaluated using surgical reports, and the other patients were evaluated using clinical findings. RESULTS: DECT was performed in 21 patients with NEC stages 2-A, 2-B and 3-A. Twelve patients (57.1%) without ischemia were followed up without surgery. Nine patients (42.9%) with ischemia on DECT were operated on, and resection and anastomosis or ileostomy and colostomy were performed. CONCLUSION: In patients with NEC, DECT significantly increases overall diagnostic confidence in assessing intestinal necrosis when compared with traditional diagnostic methods. The Scientific and Technological Research Council of Turkey 2021-10-21 /pmc/articles/PMC8742483/ /pubmed/34333905 http://dx.doi.org/10.3906/sag-2103-294 Text en Copyright © 2021 The Author(s) https://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted use and redistribution provided that the original author and source are credited.
spellingShingle Article
ÇAĞLAR, Özgür
CESUR, Emrullah
SADE, Recep
FIRINCI, Binali
KARA, Mustafa
ÇELİKKAYA, Mehmet Emin
ORAL, Akgün
YİĞİTER, Murat
ÖZMEN, Sevilay
Dual energy CT in necrotizing enterocolitis; a novel diagnostic approach
title Dual energy CT in necrotizing enterocolitis; a novel diagnostic approach
title_full Dual energy CT in necrotizing enterocolitis; a novel diagnostic approach
title_fullStr Dual energy CT in necrotizing enterocolitis; a novel diagnostic approach
title_full_unstemmed Dual energy CT in necrotizing enterocolitis; a novel diagnostic approach
title_short Dual energy CT in necrotizing enterocolitis; a novel diagnostic approach
title_sort dual energy ct in necrotizing enterocolitis; a novel diagnostic approach
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742483/
https://www.ncbi.nlm.nih.gov/pubmed/34333905
http://dx.doi.org/10.3906/sag-2103-294
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