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Dual energy CT in necrotizing enterocolitis; a novel diagnostic approach
BACKGROUND/AIM: Necrotizing enterocolitis (NEC) is one of the most important causes of morbidity and mortality in premature infants. Although there are no specific diagnostic tools, the main factors affecting prognosis are clinical and laboratory findings, and early diagnosis and treatment. In this...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Scientific and Technological Research Council of Turkey
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742483/ https://www.ncbi.nlm.nih.gov/pubmed/34333905 http://dx.doi.org/10.3906/sag-2103-294 |
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author | ÇAĞLAR, Özgür CESUR, Emrullah SADE, Recep FIRINCI, Binali KARA, Mustafa ÇELİKKAYA, Mehmet Emin ORAL, Akgün YİĞİTER, Murat ÖZMEN, Sevilay |
author_facet | ÇAĞLAR, Özgür CESUR, Emrullah SADE, Recep FIRINCI, Binali KARA, Mustafa ÇELİKKAYA, Mehmet Emin ORAL, Akgün YİĞİTER, Murat ÖZMEN, Sevilay |
author_sort | ÇAĞLAR, Özgür |
collection | PubMed |
description | BACKGROUND/AIM: Necrotizing enterocolitis (NEC) is one of the most important causes of morbidity and mortality in premature infants. Although there are no specific diagnostic tools, the main factors affecting prognosis are clinical and laboratory findings, and early diagnosis and treatment. In this study, we demonstrate the importance of dual-energy computed tomography (DECT) in confirming intestinal ischemia in neonates with NEC. MATERIALS AND METHODS: Patients diagnosed with NEC in a neonatal intensive care unit were staged according to modified Bell’s classification, and DECT was performed on patients with NEC stages 2-A, 2-B and 3-A. According to their DECT reports, these patients were then separated into two groups: those with intestinal ischemia and those without intestinal ischemia. The patients with intestinal ischemia were evaluated using surgical reports, and the other patients were evaluated using clinical findings. RESULTS: DECT was performed in 21 patients with NEC stages 2-A, 2-B and 3-A. Twelve patients (57.1%) without ischemia were followed up without surgery. Nine patients (42.9%) with ischemia on DECT were operated on, and resection and anastomosis or ileostomy and colostomy were performed. CONCLUSION: In patients with NEC, DECT significantly increases overall diagnostic confidence in assessing intestinal necrosis when compared with traditional diagnostic methods. |
format | Online Article Text |
id | pubmed-8742483 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | The Scientific and Technological Research Council of Turkey |
record_format | MEDLINE/PubMed |
spelling | pubmed-87424832022-01-20 Dual energy CT in necrotizing enterocolitis; a novel diagnostic approach ÇAĞLAR, Özgür CESUR, Emrullah SADE, Recep FIRINCI, Binali KARA, Mustafa ÇELİKKAYA, Mehmet Emin ORAL, Akgün YİĞİTER, Murat ÖZMEN, Sevilay Turk J Med Sci Article BACKGROUND/AIM: Necrotizing enterocolitis (NEC) is one of the most important causes of morbidity and mortality in premature infants. Although there are no specific diagnostic tools, the main factors affecting prognosis are clinical and laboratory findings, and early diagnosis and treatment. In this study, we demonstrate the importance of dual-energy computed tomography (DECT) in confirming intestinal ischemia in neonates with NEC. MATERIALS AND METHODS: Patients diagnosed with NEC in a neonatal intensive care unit were staged according to modified Bell’s classification, and DECT was performed on patients with NEC stages 2-A, 2-B and 3-A. According to their DECT reports, these patients were then separated into two groups: those with intestinal ischemia and those without intestinal ischemia. The patients with intestinal ischemia were evaluated using surgical reports, and the other patients were evaluated using clinical findings. RESULTS: DECT was performed in 21 patients with NEC stages 2-A, 2-B and 3-A. Twelve patients (57.1%) without ischemia were followed up without surgery. Nine patients (42.9%) with ischemia on DECT were operated on, and resection and anastomosis or ileostomy and colostomy were performed. CONCLUSION: In patients with NEC, DECT significantly increases overall diagnostic confidence in assessing intestinal necrosis when compared with traditional diagnostic methods. The Scientific and Technological Research Council of Turkey 2021-10-21 /pmc/articles/PMC8742483/ /pubmed/34333905 http://dx.doi.org/10.3906/sag-2103-294 Text en Copyright © 2021 The Author(s) https://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted use and redistribution provided that the original author and source are credited. |
spellingShingle | Article ÇAĞLAR, Özgür CESUR, Emrullah SADE, Recep FIRINCI, Binali KARA, Mustafa ÇELİKKAYA, Mehmet Emin ORAL, Akgün YİĞİTER, Murat ÖZMEN, Sevilay Dual energy CT in necrotizing enterocolitis; a novel diagnostic approach |
title | Dual energy CT in necrotizing enterocolitis; a novel diagnostic approach |
title_full | Dual energy CT in necrotizing enterocolitis; a novel diagnostic approach |
title_fullStr | Dual energy CT in necrotizing enterocolitis; a novel diagnostic approach |
title_full_unstemmed | Dual energy CT in necrotizing enterocolitis; a novel diagnostic approach |
title_short | Dual energy CT in necrotizing enterocolitis; a novel diagnostic approach |
title_sort | dual energy ct in necrotizing enterocolitis; a novel diagnostic approach |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742483/ https://www.ncbi.nlm.nih.gov/pubmed/34333905 http://dx.doi.org/10.3906/sag-2103-294 |
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