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Not all wavelengths are created equal: disinfection of SARS-CoV-2 using UVC radiation is wavelength-dependent

SARS-CoV-2 is mostly transmitted through close contact with infected people by infected aerosols and fomites. Ultraviolet subtype C (UVC) lamps and light-emitting diodes can be used to disrupt the transmission chain by disinfecting fomites, thus managing the disease outbreak progression. Here, we as...

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Detalles Bibliográficos
Autores principales: Mariita, Richard M., Peterson, James W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742593/
https://www.ncbi.nlm.nih.gov/pubmed/35018323
http://dx.doi.org/10.1099/acmi.0.000276
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author Mariita, Richard M.
Peterson, James W.
author_facet Mariita, Richard M.
Peterson, James W.
author_sort Mariita, Richard M.
collection PubMed
description SARS-CoV-2 is mostly transmitted through close contact with infected people by infected aerosols and fomites. Ultraviolet subtype C (UVC) lamps and light-emitting diodes can be used to disrupt the transmission chain by disinfecting fomites, thus managing the disease outbreak progression. Here, we assess the ultraviolet wavelengths that are most effective in inactivation of SARS-CoV-2 on fomites. Variations in UVC wavelengths impact the dose required for disinfection of SARS-CoV-2 and alter how rapidly and effectively disruption of the virus transmission chain can be achieved. This study reveals that shorter wavelengths (254–268 nm) take a maximum of 6.25 mJ/cm(2) over 5 s to obtain a target SARS-CoV-2 reduction of 99.9%. Longer wavelengths, like 280 nm, take longer irradiation time and higher dose to inactivate SARS-CoV-2. These observations emphasize that SARS-CoV-2 inactivation is wavelength-dependent.
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spelling pubmed-87425932022-01-10 Not all wavelengths are created equal: disinfection of SARS-CoV-2 using UVC radiation is wavelength-dependent Mariita, Richard M. Peterson, James W. Access Microbiol Short Communications SARS-CoV-2 is mostly transmitted through close contact with infected people by infected aerosols and fomites. Ultraviolet subtype C (UVC) lamps and light-emitting diodes can be used to disrupt the transmission chain by disinfecting fomites, thus managing the disease outbreak progression. Here, we assess the ultraviolet wavelengths that are most effective in inactivation of SARS-CoV-2 on fomites. Variations in UVC wavelengths impact the dose required for disinfection of SARS-CoV-2 and alter how rapidly and effectively disruption of the virus transmission chain can be achieved. This study reveals that shorter wavelengths (254–268 nm) take a maximum of 6.25 mJ/cm(2) over 5 s to obtain a target SARS-CoV-2 reduction of 99.9%. Longer wavelengths, like 280 nm, take longer irradiation time and higher dose to inactivate SARS-CoV-2. These observations emphasize that SARS-CoV-2 inactivation is wavelength-dependent. Microbiology Society 2021-11-02 /pmc/articles/PMC8742593/ /pubmed/35018323 http://dx.doi.org/10.1099/acmi.0.000276 Text en © 2021 The Authors https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License.
spellingShingle Short Communications
Mariita, Richard M.
Peterson, James W.
Not all wavelengths are created equal: disinfection of SARS-CoV-2 using UVC radiation is wavelength-dependent
title Not all wavelengths are created equal: disinfection of SARS-CoV-2 using UVC radiation is wavelength-dependent
title_full Not all wavelengths are created equal: disinfection of SARS-CoV-2 using UVC radiation is wavelength-dependent
title_fullStr Not all wavelengths are created equal: disinfection of SARS-CoV-2 using UVC radiation is wavelength-dependent
title_full_unstemmed Not all wavelengths are created equal: disinfection of SARS-CoV-2 using UVC radiation is wavelength-dependent
title_short Not all wavelengths are created equal: disinfection of SARS-CoV-2 using UVC radiation is wavelength-dependent
title_sort not all wavelengths are created equal: disinfection of sars-cov-2 using uvc radiation is wavelength-dependent
topic Short Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742593/
https://www.ncbi.nlm.nih.gov/pubmed/35018323
http://dx.doi.org/10.1099/acmi.0.000276
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