SLCO1B1 *15 allele is associated with methotrexate‐induced nausea in pediatric patients with inflammatory bowel disease

Low‐dose methotrexate (MTX) is an immunosuppressant used to treat inflammatory bowel disease (IBD). SLCO1B1 genetic variation has been associated with delayed MTX clearance and increased toxicity. The purpose of this study was to evaluate the association between SLCO1B1 genetic variation and MTX‐ind...

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Detalles Bibliográficos
Autores principales: Mehta, Rishi S., Taylor, Zachary L., Martin, Lisa J., Rosen, Michael J., Ramsey, Laura B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742639/
https://www.ncbi.nlm.nih.gov/pubmed/34423897
http://dx.doi.org/10.1111/cts.13130

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742639/
https://www.ncbi.nlm.nih.gov/pubmed/34423897
http://dx.doi.org/10.1111/cts.13130

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