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SLCO1B1 *15 allele is associated with methotrexate‐induced nausea in pediatric patients with inflammatory bowel disease
Low‐dose methotrexate (MTX) is an immunosuppressant used to treat inflammatory bowel disease (IBD). SLCO1B1 genetic variation has been associated with delayed MTX clearance and increased toxicity. The purpose of this study was to evaluate the association between SLCO1B1 genetic variation and MTX‐ind...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742639/ https://www.ncbi.nlm.nih.gov/pubmed/34423897 http://dx.doi.org/10.1111/cts.13130 |