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Limited sampling strategies for estimation of tacrolimus exposure in kidney transplant recipients receiving extended‐release tacrolimus preparation

Tacrolimus is the key component of most contemporary immunosuppressive drug regimens for the prevention of transplant rejection. Area under the concentration time curve over 24 h (AUC(0–24)) predicts efficacy, but predose (trough) tacrolimus blood concentration (C(0)) is currently used to guide dosi...

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Detalles Bibliográficos
Autores principales: El‐Nahhas, Toqa, Popoola, Joyce, MacPhee, Iain, Johnston, Atholl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742643/
https://www.ncbi.nlm.nih.gov/pubmed/34780122
http://dx.doi.org/10.1111/cts.12990