Cargando…

Microphysiological systems in absorption, distribution, metabolism, and elimination sciences

The use of microphysiological systems (MPS) to support absorption, distribution, metabolism, and elimination (ADME) sciences has grown substantially in the last decade, in part driven by regulatory demands to move away from traditional animal‐based safety assessment studies and industry desires to d...

Descripción completa

Detalles Bibliográficos
Autores principales:	Van Ness, Kirk P., Cesar, Francine, Yeung, Catherine K., Himmelfarb, Jonathan, Kelly, Edward J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742652/ https://www.ncbi.nlm.nih.gov/pubmed/34378335 http://dx.doi.org/10.1111/cts.13132

Ejemplares similares

Bridging the gap between in silico and in vivo by modeling opioid disposition in a kidney proximal tubule microphysiological system
por: Imaoka, Tomoki, et al.
Publicado: (2021)

Translational Assessment of Drug‐Induced Proximal Tubule Injury Using a Kidney Microphysiological System
por: Maass, Christian, et al.
Publicado: (2019)

Technology Transfer of the Microphysiological Systems: A Case Study of the Human Proximal Tubule Tissue Chip
por: Sakolish, Courtney, et al.
Publicado: (2018)

Reevaluating the Role of Megalin in Renal Vitamin D Homeostasis Using a Human Cell-Derived Microphysiological System
por: Chapron, Brian D., et al.
Publicado: (2018)

Microphysiological systems
por: Hickman, James J., et al.
Publicado: (2019)

Functional Coupling of Human Microphysiology Systems: Intestine, Liver, Kidney Proximal Tubule, Blood-Brain Barrier and Skeletal Muscle
por: Vernetti, Lawrence, et al.
Publicado: (2017)

Corrigendum: Functional Coupling of Human Microphysiology Systems: Intestine, Liver, Kidney Proximal Tubule, Blood-Brain Barrier and Skeletal Muscle
por: Vernetti, Lawrence, et al.
Publicado: (2017)

Advancing Regulatory Science Through Innovation: In Vitro Microphysiological Systems
por: Fitzpatrick, Suzanne, et al.
Publicado: (2018)

Kidney Organoid and Microphysiological Kidney Chip Models to Accelerate Drug Development and Reduce Animal Testing
por: Chen, Wei-Yang, et al.
Publicado: (2021)

Engineering challenges in microphysiological systems
por: Zhang, Yu Shrike
Publicado: (2017)

Liver microphysiological platforms for drug metabolism applications
por: Kulsharova, Gulsim, et al.
Publicado: (2021)

Interconnected Microphysiological Systems for Quantitative Biology and Pharmacology Studies
por: Edington, Collin D., et al.
Publicado: (2018)

The Development of Controllable Magnetic Driven Microphysiological System
por: Yang, Jia-Wei, et al.
Publicado: (2019)

A Microphysiological System for Studying Nonalcoholic Steatohepatitis
por: Kostrzewski, Tomasz, et al.
Publicado: (2019)

Stem cell-based vascularization of microphysiological systems
por: Browne, Shane, et al.
Publicado: (2021)

Microphysiological Systems for Neurodegenerative Diseases in Central Nervous System
por: Bae, Mihyeon, et al.
Publicado: (2020)

3D organ-on-a-chip: The convergence of microphysiological systems and organoids
por: Baptista, Leandra S., et al.
Publicado: (2022)

Scalable microphysiological system to model three-dimensional blood vessels
por: de Graaf, Mees N. S., et al.
Publicado: (2019)

Microphysiological systems and low-cost microfluidic platform with analytics
por: Smith, Alec ST, et al.
Publicado: (2013)

Human Vascular Microphysiological System for in vitro Drug Screening
por: Fernandez, C. E., et al.
Publicado: (2016)

The ascendance of microphysiological systems to solve the drug testing dilemma
por: Dehne, Eva-Maria, et al.
Publicado: (2017)

Modular Microphysiological System for Modeling of Biologic Barrier Function
por: Ishahak, Matthew, et al.
Publicado: (2020)

Liver Microphysiological Systems for Predicting and Evaluating Drug Effects
por: Ribeiro, Alexandre J. S., et al.
Publicado: (2019)

Harnessing the power of microphysiological systems for COVID-19 research
por: Kleinstreuer, Nicole, et al.
Publicado: (2021)

Chemical reactivity-absorption, retention, metabolism, and elimination of hexachlorocyclopentadiene.
por: Mehendale, H M
Publicado: (1977)

On the Absorption and Elimination of Quinine
Publicado: (1881)

Characterizing the reproducibility in using a liver microphysiological system for assaying drug toxicity, metabolism, and accumulation
por: Rubiano, Andrés, et al.
Publicado: (2021)

Instrumented Microphysiological Systems for Real-Time Measurement and Manipulation of Cellular Electrochemical Processes
por: Soucy, Jonathan R., et al.
Publicado: (2019)

Human Microphysiological Systems and Organoids as in Vitro Models for Toxicological Studies
por: Truskey, George A.
Publicado: (2018)

Farewell to Animal Testing: Innovations on Human Intestinal Microphysiological Systems
por: Kang, Tae Hyun, et al.
Publicado: (2016)

Microphysiological Systems (“Organs‐on‐Chips”) for Drug Efficacy and Toxicity Testing
por: Low, LA, et al.
Publicado: (2017)

Organoids and Microphysiological Systems: New Tools for Ophthalmic Drug Discovery
por: Bai, Jing, et al.
Publicado: (2020)

Tissue Chips and Microphysiological Systems for Disease Modeling and Drug Testing
por: Donoghue, Leslie, et al.
Publicado: (2021)

Critical Considerations for the Design of Multi-Organ Microphysiological Systems (MPS)
por: Malik, Mridu, et al.
Publicado: (2021)

Light-triggered cardiac microphysiological model
por: Vurro, V., et al.
Publicado: (2023)

Establishing quasi-steady state operations of microphysiological systems (MPS) using tissue-specific metabolic dependencies
por: Maass, Christian, et al.
Publicado: (2018)

Effects of chronic kidney disease and uremia on hepatic drug metabolism and transport
por: Yeung, Catherine K., et al.
Publicado: (2013)

Universal Micromachining Platform and Basic Technologies for the Manufacture and Marking of Microphysiological Systems
por: Günther, Katja, et al.
Publicado: (2017)

Applications of the microphysiology systems database for experimental ADME-Tox and disease models
por: Schurdak, Mark, et al.
Publicado: (2020)

Modeling statin myopathy in a human skeletal muscle microphysiological system
por: Ananthakumar, Anandita, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_7et3ohlkl64mmb8toib2mjk7i1