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Leptin hormone and its effectiveness in reproduction, metabolism, immunity, diabetes, hopes and ambitions

Leptin is a hormone derived from adipose tissue and the small intestine, mainly in enterocytes; it helps regulate the energy balance by suppressing hunger, resulting in decreased fat mass in adipocytes. Leptin has specific receptors in the ventromedial and arcuate nuclei and other parts of the hypot...

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Autores principales: Al-hussaniy, Hany Akeel, Alburghaif, Ali Hikmate, Naji, Meena Akeel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Carol Davila University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742898/
https://www.ncbi.nlm.nih.gov/pubmed/35027962
http://dx.doi.org/10.25122/jml-2021-0153
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author Al-hussaniy, Hany Akeel
Alburghaif, Ali Hikmate
Naji, Meena Akeel
author_facet Al-hussaniy, Hany Akeel
Alburghaif, Ali Hikmate
Naji, Meena Akeel
author_sort Al-hussaniy, Hany Akeel
collection PubMed
description Leptin is a hormone derived from adipose tissue and the small intestine, mainly in enterocytes; it helps regulate the energy balance by suppressing hunger, resulting in decreased fat mass in adipocytes. Leptin has specific receptors in the ventromedial and arcuate nuclei and other parts of the hypothalamus and the feeding center in the ventral tegmental area. It also plays a role in regulatory aspects other than fat cells, such as obesity, which is linked to a loss of sensitivity of leptin receptors, resulting in an inability to produce satiety and an increase in food intake. Moreover, leptin plays a part in lactation, bone density, the immune system, diabetes treatments, and hypertriglyceridemia. The latest studies in leptin suggest that an analog of leptin may treat DM and hypertriglyceridemia. Further research should be conducted on the effectiveness of leptin on other related diseases.
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spelling pubmed-87428982022-01-12 Leptin hormone and its effectiveness in reproduction, metabolism, immunity, diabetes, hopes and ambitions Al-hussaniy, Hany Akeel Alburghaif, Ali Hikmate Naji, Meena Akeel J Med Life Review Leptin is a hormone derived from adipose tissue and the small intestine, mainly in enterocytes; it helps regulate the energy balance by suppressing hunger, resulting in decreased fat mass in adipocytes. Leptin has specific receptors in the ventromedial and arcuate nuclei and other parts of the hypothalamus and the feeding center in the ventral tegmental area. It also plays a role in regulatory aspects other than fat cells, such as obesity, which is linked to a loss of sensitivity of leptin receptors, resulting in an inability to produce satiety and an increase in food intake. Moreover, leptin plays a part in lactation, bone density, the immune system, diabetes treatments, and hypertriglyceridemia. The latest studies in leptin suggest that an analog of leptin may treat DM and hypertriglyceridemia. Further research should be conducted on the effectiveness of leptin on other related diseases. Carol Davila University Press 2021 /pmc/articles/PMC8742898/ /pubmed/35027962 http://dx.doi.org/10.25122/jml-2021-0153 Text en ©2021 JOURNAL of MEDICINE and LIFE https://creativecommons.org/licenses/by/3.0/This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/ (https://creativecommons.org/licenses/by/3.0/) ), which permits unrestricted use and redistribution provided that the original author and source are credited.
spellingShingle Review
Al-hussaniy, Hany Akeel
Alburghaif, Ali Hikmate
Naji, Meena Akeel
Leptin hormone and its effectiveness in reproduction, metabolism, immunity, diabetes, hopes and ambitions
title Leptin hormone and its effectiveness in reproduction, metabolism, immunity, diabetes, hopes and ambitions
title_full Leptin hormone and its effectiveness in reproduction, metabolism, immunity, diabetes, hopes and ambitions
title_fullStr Leptin hormone and its effectiveness in reproduction, metabolism, immunity, diabetes, hopes and ambitions
title_full_unstemmed Leptin hormone and its effectiveness in reproduction, metabolism, immunity, diabetes, hopes and ambitions
title_short Leptin hormone and its effectiveness in reproduction, metabolism, immunity, diabetes, hopes and ambitions
title_sort leptin hormone and its effectiveness in reproduction, metabolism, immunity, diabetes, hopes and ambitions
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742898/
https://www.ncbi.nlm.nih.gov/pubmed/35027962
http://dx.doi.org/10.25122/jml-2021-0153
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