Trans-ethnic Mendelian-randomization study reveals causal relationships between cardiometabolic factors and chronic kidney disease

BACKGROUND: This study was to systematically test whether previously reported risk factors for chronic kidney disease (CKD) are causally related to CKD in European and East Asian ancestries using Mendelian randomization. METHODS: A total of 45 risk factors with genetic data in European ancestry and...

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Detalles Bibliográficos
Autores principales: Zheng, Jie, Zhang, Yuemiao, Rasheed, Humaira, Walker, Venexia, Sugawara, Yuka, Li, Jiachen, Leng, Yue, Elsworth, Benjamin, Wootton, Robyn E, Fang, Si, Yang, Qian, Burgess, Stephen, Haycock, Philip C, Borges, Maria Carolina, Cho, Yoonsu, Carnegie, Rebecca, Howell, Amy, Robinson, Jamie, Thomas, Laurent F, Brumpton, Ben Michael, Hveem, Kristian, Hallan, Stein, Franceschini, Nora, Morris, Andrew P, Köttgen, Anna, Pattaro, Cristian, Wuttke, Matthias, Yamamoto, Masayuki, Kashihara, Naoki, Akiyama, Masato, Kanai, Masahiro, Matsuda, Koichi, Kamatani, Yoichiro, Okada, Yukinori, Walters, Robin, Millwood, Iona Y, Chen, Zhengming, Davey Smith, George, Barbour, Sean, Yu, Canqing, Åsvold, Bjørn Olav, Zhang, Hong, Gaunt, Tom R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Mendelian Randomization
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8743120/
https://www.ncbi.nlm.nih.gov/pubmed/34999880
http://dx.doi.org/10.1093/ije/dyab203

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