Delayed viral clearance despite high number of activated T cells during the acute phase in Argentinean patients with hantavirus pulmonary syndrome

BACKGROUND: The hallmarks of HPS are increase of vascular permeability and endothelial dysfunction. Although an exacerbated immune response is thought to be implicated in pathogenesis, clear evidence is still elusive. As orthohantaviruses are not cytopathic CD8(+) T cells are believed to be the cent...

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Detalles Bibliográficos
Autores principales: Iglesias, Ayelén Aluminé, Períolo, Natalia, Bellomo, Carla María, Lewis, Lorena Cecilia, Olivera, Camila Paula, Anselmo, Constanza Rosario, García, Marina, Coelho, Rocío María, Alonso, Daniel Oscar, Dighero-Kemp, Bonnie, Sharma, Heema, Kuhn, Jens H., Di Paola, Nicholas, Sanchez-Lockhart, Mariano, Palacios, Gustavo, Schierloh, Luis Pablo, Martínez, Valeria Paula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8743200/
https://www.ncbi.nlm.nih.gov/pubmed/34986457
http://dx.doi.org/10.1016/j.ebiom.2021.103765

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