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Multidisciplinary treatment of advanced or recurrent solid pseudopapillary neoplasm of the pancreas: three case reports
BACKGROUND: Solid pseudopapillary neoplasm (SPN) is a rare pancreatic tumor that predominantly affects young females. Prognosis is excellent; however, 10–15% of patients show metastasis at the time of surgery or develop tumor recurrence after pancreatectomy. CASE PRESENTATION: We reviewed the clinic...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8743312/ https://www.ncbi.nlm.nih.gov/pubmed/35001187 http://dx.doi.org/10.1186/s40792-022-01358-0 |
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author | Tanoue, Kiyonori Mataki, Yuko Kurahara, Hiroshi Idichi, Tetsuya Kawasaki, Yota Yamasaki, Yoichi Kita, Yoshiaki Hozaka, Yuto Oi, Hideyuki Nakajo, Akihiro Arigami, Takaaki Maemura, Kosei Ohtsuka, Takao |
author_facet | Tanoue, Kiyonori Mataki, Yuko Kurahara, Hiroshi Idichi, Tetsuya Kawasaki, Yota Yamasaki, Yoichi Kita, Yoshiaki Hozaka, Yuto Oi, Hideyuki Nakajo, Akihiro Arigami, Takaaki Maemura, Kosei Ohtsuka, Takao |
author_sort | Tanoue, Kiyonori |
collection | PubMed |
description | BACKGROUND: Solid pseudopapillary neoplasm (SPN) is a rare pancreatic tumor that predominantly affects young females. Prognosis is excellent; however, 10–15% of patients show metastasis at the time of surgery or develop tumor recurrence after pancreatectomy. CASE PRESENTATION: We reviewed the clinical course of three patients with advanced or recurrent SPN and subsequently underwent multidisciplinary treatment at our institution between 2002 and 2019. The primary tumor was resected in all three patients, and metastases were also resected if indicated. Intensive combined therapy, including re-resection, chemotherapy, ablation, arterial chemoembolization, and radiation therapy, allowed all patients to survive for a long time. The literature review showed that resection seems to be more effective than other treatments for metastatic SPN. CONCLUSIONS: Multidisciplinary treatment, including resection, may improve the prognosis of patients with SPN with recurrence or metastasis. |
format | Online Article Text |
id | pubmed-8743312 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-87433122022-01-20 Multidisciplinary treatment of advanced or recurrent solid pseudopapillary neoplasm of the pancreas: three case reports Tanoue, Kiyonori Mataki, Yuko Kurahara, Hiroshi Idichi, Tetsuya Kawasaki, Yota Yamasaki, Yoichi Kita, Yoshiaki Hozaka, Yuto Oi, Hideyuki Nakajo, Akihiro Arigami, Takaaki Maemura, Kosei Ohtsuka, Takao Surg Case Rep Case Report BACKGROUND: Solid pseudopapillary neoplasm (SPN) is a rare pancreatic tumor that predominantly affects young females. Prognosis is excellent; however, 10–15% of patients show metastasis at the time of surgery or develop tumor recurrence after pancreatectomy. CASE PRESENTATION: We reviewed the clinical course of three patients with advanced or recurrent SPN and subsequently underwent multidisciplinary treatment at our institution between 2002 and 2019. The primary tumor was resected in all three patients, and metastases were also resected if indicated. Intensive combined therapy, including re-resection, chemotherapy, ablation, arterial chemoembolization, and radiation therapy, allowed all patients to survive for a long time. The literature review showed that resection seems to be more effective than other treatments for metastatic SPN. CONCLUSIONS: Multidisciplinary treatment, including resection, may improve the prognosis of patients with SPN with recurrence or metastasis. Springer Berlin Heidelberg 2022-01-10 /pmc/articles/PMC8743312/ /pubmed/35001187 http://dx.doi.org/10.1186/s40792-022-01358-0 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Case Report Tanoue, Kiyonori Mataki, Yuko Kurahara, Hiroshi Idichi, Tetsuya Kawasaki, Yota Yamasaki, Yoichi Kita, Yoshiaki Hozaka, Yuto Oi, Hideyuki Nakajo, Akihiro Arigami, Takaaki Maemura, Kosei Ohtsuka, Takao Multidisciplinary treatment of advanced or recurrent solid pseudopapillary neoplasm of the pancreas: three case reports |
title | Multidisciplinary treatment of advanced or recurrent solid pseudopapillary neoplasm of the pancreas: three case reports |
title_full | Multidisciplinary treatment of advanced or recurrent solid pseudopapillary neoplasm of the pancreas: three case reports |
title_fullStr | Multidisciplinary treatment of advanced or recurrent solid pseudopapillary neoplasm of the pancreas: three case reports |
title_full_unstemmed | Multidisciplinary treatment of advanced or recurrent solid pseudopapillary neoplasm of the pancreas: three case reports |
title_short | Multidisciplinary treatment of advanced or recurrent solid pseudopapillary neoplasm of the pancreas: three case reports |
title_sort | multidisciplinary treatment of advanced or recurrent solid pseudopapillary neoplasm of the pancreas: three case reports |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8743312/ https://www.ncbi.nlm.nih.gov/pubmed/35001187 http://dx.doi.org/10.1186/s40792-022-01358-0 |
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