Cargando…

Effects of a protein‐restricted diet on body weight and serum tyrosine concentrations in patients with alkaptonuria

In an open‐label, controlled study of nitisinone in alkaptonuria (SONIA 2), patients were advised to lower dietary protein intake to reduce serum tyrosine (s‐Tyr) levels and the risk of keratopathy. A body weight increase was observed in the nitisinone‐treated patients but not in the control group....

Descripción completa

Detalles Bibliográficos
Autores principales:	Olsson, Birgitta, Ranganath, Lakshminarayan, Arnoux, Jean‐Baptiste, Imrich, Richard, Milan, Anna, Rudebeck, Mattias
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Inc. 2021
Materias:	Research Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8743336/ https://www.ncbi.nlm.nih.gov/pubmed/35028270 http://dx.doi.org/10.1002/jmd2.12255

Ejemplares similares

Improving the clinical accuracy and flexibility of the Alkaptonuria severity score index
por: Cant, Harriet E. O., et al.
Publicado: (2022)

Revisiting Quantification of Phenylalanine/Tyrosine Flux in the Ochronotic Pathway during Long-Term Nitisinone Treatment of Alkaptonuria
por: Ranganath, Lakshminarayan R., et al.
Publicado: (2022)

Analysis of the Phenotype Differences in Siblings with Alkaptonuria
por: Zatkova, Andrea, et al.
Publicado: (2022)

Comparing the Phenylalanine/Tyrosine Pathway and Related Factors between Keratopathy and No-Keratopathy Groups as Well as between Genders in Alkaptonuria during Nitisinone Treatment
por: Ranganath, Lakshminarayan R., et al.
Publicado: (2022)

Radiological evolution of spinal disease in alkaptonuria and the effect of nitisinone
por: Imrich, Richard, et al.
Publicado: (2022)

Nitisinone Treatment Affects Biomarkers of Bone and Cartilage Remodelling in Alkaptonuria Patients
por: Genovese, Federica, et al.
Publicado: (2023)

A patient survey on the impact of alkaptonuria symptoms as perceived by the patients and their experiences of receiving diagnosis and care
por: Rudebeck, Mattias, et al.
Publicado: (2020)

Determinants of tyrosinaemia during nitisinone therapy in alkaptonuria
por: Ranganath, L. R., et al.
Publicado: (2022)

Dietary restriction of tyrosine and phenylalanine lowers tyrosinemia associated with nitisinone therapy of alkaptonuria
por: Hughes, Juliette H., et al.
Publicado: (2020)

Characterization of changes in the tyrosine pathway by 24-h profiling during nitisinone treatment in alkaptonuria
por: Ranganath, L.R., et al.
Publicado: (2022)

Alkaptonuria: Current Perspectives
por: Zatkova, Andrea, et al.
Publicado: (2020)

Development of an Effective Therapy for Alkaptonuria – Lessons for Osteoarthritis
por: Gallagher, James A., et al.
Publicado: (2021)

Increased prevalence of Parkinson's disease in alkaptonuria
por: Ranganath, Lakshminarayan, et al.
Publicado: (2023)

Metabolomic studies in the inborn error of metabolism alkaptonuria reveal new biotransformations in tyrosine metabolism
por: Norman, Brendan P., et al.
Publicado: (2021)

Reversal of ochronotic pigmentation in alkaptonuria following nitisinone therapy: Analysis of data from the United Kingdom National Alkaptonuria Centre
por: Ranganath, Lakshminarayan R., et al.
Publicado: (2020)

Comparing nitisinone 2 mg and 10 mg in the treatment of alkaptonuria—An approach using statistical modelling
por: Ranganath, Lakshminarayan R., et al.
Publicado: (2021)

Quantification of the flux of tyrosine pathway metabolites during nitisinone treatment of Alkaptonuria
por: Milan, A. M., et al.
Publicado: (2019)

Clinical development of nitisinone for alkaptonuria (developakure) - a rare disease clinical trials design
por: Psarelli, Eftychia Eirini, et al.
Publicado: (2013)

Impact of Nitisinone on the Cerebrospinal Fluid Metabolome of a Murine Model of Alkaptonuria
por: Davison, Andrew S., et al.
Publicado: (2022)

Effects of Nitisinone on Oxidative and Inflammatory Markers in Alkaptonuria: Results from SONIA1 and SONIA2 Studies
por: Braconi, Daniela, et al.
Publicado: (2022)

First decade anniversary of the United Kingdom National Alkaptonuria Centre
por: Khedr, Milad, et al.
Publicado: (2023)

Evaluation of the serum metabolome of patients with alkaptonuria before and after two years of treatment with nitisinone using LC‐QTOF‐MS
por: Davison, Andrew S., et al.
Publicado: (2019)

Fatal oxidative haemolysis and methaemoglobinaemia in a patient with alkaptonuria and acute kidney injury
por: Mullan, Adam, et al.
Publicado: (2015)

Comprehensive Biotransformation Analysis of Phenylalanine-Tyrosine Metabolism Reveals Alternative Routes of Metabolite Clearance in Nitisinone-Treated Alkaptonuria
por: Norman, Brendan P., et al.
Publicado: (2022)

Vitiligo, alkaptonuria, and nitisinone—A report of three families and review of the literature
por: Ranganath, Lakshminarayan, et al.
Publicado: (2021)

Association of alkaptonuria and low dose nitisinone therapy with cataract formation in a large cohort of patients
por: Ahmad, Mohammad S. Z., et al.
Publicado: (2022)

Pigmentation Chemistry and Radical‐Based Collagen Degradation in Alkaptonuria and Osteoarthritic Cartilage
por: Chow, Wing Ying, et al.
Publicado: (2020)

Long‐term low dose nitisinone therapy in adults with alkaptonuria shows no cognitive decline or increased severity of depression
por: Davison, Andrew S., et al.
Publicado: (2022)

Clinical development innovation in rare diseases: lessons learned and best practices from the DevelopAKUre consortium
por: Rudebeck, Mattias, et al.
Publicado: (2021)

A case report of pregnancy in untreated alkaptonuria – Focus on urinary tissue remodelling markers
por: Ranganath, L.R., et al.
Publicado: (2021)

ALKAPTONURIA
por: Tharini, GK, et al.
Publicado: (2011)

Alkaptonuria
Publicado: (1899)

Serum Oxidative-Antioxidative Status in Patients With Alkaptonuria
por: Albatayneh, Eman M., et al.
Publicado: (2019)

Evaluation of Homogentisic Acid, a Prospective Antibacterial Agent Highlighted by the Suitability of Nitisinone in Alkaptonuria 2 (SONIA 2) Clinical Trial
por: Ooi, Nicola, et al.
Publicado: (2023)

The nutritional status of people with alkaptonuria: An exploratory analysis suggests a protein/energy dilemma
por: Judd, Shirley, et al.
Publicado: (2020)

Data on items of AKUSSI in Alkaptonuria collected over three years from the United Kingdom National Alkaptonuria Centre and the impact of nitisinone
por: Griffin, R., et al.
Publicado: (2018)

Fatal acute haemolysis and methaemoglobinaemia in a man with renal failure and Alkaptonuria – Is nitisinone the solution?
por: Davison, A.S., et al.
Publicado: (2020)

ß-thalassemia and alkaptonuria
por: Yasri, Sora, et al.
Publicado: (2014)

Alkaptonuria - Case report
por: Craide, Fernanda Helena, et al.
Publicado: (2014)

A Case of Alkaptonuria
por: Sinha, H. K.
Publicado: (1930)

Cannot write session to /tmp/vufind_sessions/sess_cde06d96gp6va8k6i4j3d8t3hl