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Reasons in favour of universal vaccination campaign against COVID-19 in the pediatric population

BACKGROUND: Despite the growing evidence of the extreme efficacy of COVID-19 vaccines in adults and the elderly, the administration of the same prophylactic measures to pediatric subjects is debated by some parents and by a number of researchers. The aim of this manuscript is to explain the reasons...

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Autores principales: Principi, Nicola, Esposito, Susanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8743738/
https://www.ncbi.nlm.nih.gov/pubmed/35012590
http://dx.doi.org/10.1186/s13052-021-01192-4
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author Principi, Nicola
Esposito, Susanna
author_facet Principi, Nicola
Esposito, Susanna
author_sort Principi, Nicola
collection PubMed
description BACKGROUND: Despite the growing evidence of the extreme efficacy of COVID-19 vaccines in adults and the elderly, the administration of the same prophylactic measures to pediatric subjects is debated by some parents and by a number of researchers. The aim of this manuscript is to explain the reasons for overcoming hesitancy towards COVID-19 vaccination in children and adolescents and to highlight the importance of universal COVID-19 vaccination in the pediatric population. MAIN FINDINGS: Recent epidemiological data suggest that the risk that a child with COVID-19 is hospitalized or admitted to the pediatric intensive care unit is greater than initially thought. Children may also suffer from long COVID and school closure because of COVID-19 can cause relevant mental health problems in the pediatric population. Placebo-controlled, observer-blinded, clinical trials showed appropriate efficacy, safety and tolerability of authorized mRNA COVID-19 vaccines in children and adolescents 12–17 years old. Vaccination in children younger than 12 years of age will allow further benefits . CONCLUSIONS: COVID-19 vaccine administration seems mandatory in all the children and adolescents because of COVID-19 related complications as well as the efficacy, safety and tolerability of COVID-19 vaccines in this population. Due to the recent approval of COVID-9 vaccines for children 5–10 years old, it is desirable that vaccine opponents can understand how important is the universal immunization against COVID-19 for the pediatric subjects.
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spelling pubmed-87437382022-01-10 Reasons in favour of universal vaccination campaign against COVID-19 in the pediatric population Principi, Nicola Esposito, Susanna Ital J Pediatr Debate BACKGROUND: Despite the growing evidence of the extreme efficacy of COVID-19 vaccines in adults and the elderly, the administration of the same prophylactic measures to pediatric subjects is debated by some parents and by a number of researchers. The aim of this manuscript is to explain the reasons for overcoming hesitancy towards COVID-19 vaccination in children and adolescents and to highlight the importance of universal COVID-19 vaccination in the pediatric population. MAIN FINDINGS: Recent epidemiological data suggest that the risk that a child with COVID-19 is hospitalized or admitted to the pediatric intensive care unit is greater than initially thought. Children may also suffer from long COVID and school closure because of COVID-19 can cause relevant mental health problems in the pediatric population. Placebo-controlled, observer-blinded, clinical trials showed appropriate efficacy, safety and tolerability of authorized mRNA COVID-19 vaccines in children and adolescents 12–17 years old. Vaccination in children younger than 12 years of age will allow further benefits . CONCLUSIONS: COVID-19 vaccine administration seems mandatory in all the children and adolescents because of COVID-19 related complications as well as the efficacy, safety and tolerability of COVID-19 vaccines in this population. Due to the recent approval of COVID-9 vaccines for children 5–10 years old, it is desirable that vaccine opponents can understand how important is the universal immunization against COVID-19 for the pediatric subjects. BioMed Central 2022-01-10 /pmc/articles/PMC8743738/ /pubmed/35012590 http://dx.doi.org/10.1186/s13052-021-01192-4 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Debate
Principi, Nicola
Esposito, Susanna
Reasons in favour of universal vaccination campaign against COVID-19 in the pediatric population
title Reasons in favour of universal vaccination campaign against COVID-19 in the pediatric population
title_full Reasons in favour of universal vaccination campaign against COVID-19 in the pediatric population
title_fullStr Reasons in favour of universal vaccination campaign against COVID-19 in the pediatric population
title_full_unstemmed Reasons in favour of universal vaccination campaign against COVID-19 in the pediatric population
title_short Reasons in favour of universal vaccination campaign against COVID-19 in the pediatric population
title_sort reasons in favour of universal vaccination campaign against covid-19 in the pediatric population
topic Debate
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8743738/
https://www.ncbi.nlm.nih.gov/pubmed/35012590
http://dx.doi.org/10.1186/s13052-021-01192-4
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