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Exosomes from adipose-derived mesenchymal stem cells alleviate sepsis-induced lung injury in mice by inhibiting the secretion of IL-27 in macrophages

Acute lung injury (ALI) represents a frequent sepsis-induced inflammatory disorder. Mesenchymal stromal cells (MSCs) elicit anti-inflammatory effects in sepsis. This study investigated the mechanism of exosomes from adipose-derived MSCs (ADMSCs) in sepsis-induced ALI. The IL-27r(−/−) (WSX-1 knockout...

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Detalles Bibliográficos
Autores principales:	Wang, Xiaoyan, Liu, Danyong, Zhang, XiHe, Yang, LiuMing, Xia, Zhengyuan, Zhang, Quanfu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744023/ https://www.ncbi.nlm.nih.gov/pubmed/35013123 http://dx.doi.org/10.1038/s41420-021-00785-6

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