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Multiple secondary outcome analyses: precise interpretation is important
Analysis of multiple secondary outcomes in a clinical trial leads to an increased probability of at least one false significant result among all secondary outcomes studied. In this paper, we question the notion that that if no multiplicity adjustment has been applied to multiple secondary outcome an...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744058/ https://www.ncbi.nlm.nih.gov/pubmed/35012627 http://dx.doi.org/10.1186/s13063-021-05975-2 |